2,5-DiMethyl Celecoxib

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Names

[ CAS No. ]:
457639-26-8

[ Name ]:
2,5-DiMethyl Celecoxib

[Synonym ]:
2,5-Dimethyl Celecoxib
4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide
Benzenesulfonamide, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-
2,5-Dimethyl-celecoxib

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
516.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H16F3N3O2S

[ Molecular Weight ]:
395.399

[ Flash Point ]:
266.3±32.9 °C

[ Exact Mass ]:
395.091522

[ PSA ]:
86.36000

[ LogP ]:
4.67

[ Appearance of Characters ]:
white to beige

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.600

[ Storage condition ]:
room temp

[ Water Solubility ]:
DMSO: soluble20mg/mL, clear

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1 / PGIII

Articles

SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis.

Mol. Biol. Cell 25(18) , 2828-39, (2014)

Endoplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodegeneration, cardiovascular diseases, and diabetes. Temporally defining calcium dysregulation during...

COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells.

Exp. Cell Res. 330(2) , 451-9, (2014)

In the present study, we investigated whether celecoxib could induce the expression of NKG2D ligands in clonogenic colon cancer cells, and increase their susceptibility to NK cell-mediated cell death....

Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanisms.

Int. J. Oncol. 46(3) , 1393-404, (2015)

Celecoxib plays antitumor roles via multiple mechanisms in a variety of human cancers. The aim of this study was to clarify the mechanism of action of celecoxib in canine mammary tumors. We examined t...


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Related Compounds

  • 2,5-dimethyl-3-(4-nitronaphthalen-1-yl)pyrrolidine
  • 2,5-Dimethyl-1,3-thiazole
  • 2,5-dimethyl-1-phenyl-piperidin-4-one
  • 2,5-dimethyl-4-(morpholinomethyl)phenol hydrochloride
  • 2,5-dimethyl-6-oxo-3H-pyrimidine-4-carboxylic acid
  • 2,5-dimethyl-4-nitro-1H-benzimidazole
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine