2,5-DiMethyl Celecoxib
2,5-DiMethyl Celecoxib structure
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Common Name | 2,5-DiMethyl Celecoxib | ||
|---|---|---|---|---|
| CAS Number | 457639-26-8 | Molecular Weight | 395.399 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 516.7±60.0 °C at 760 mmHg | |
| Molecular Formula | C18H16F3N3O2S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 266.3±32.9 °C | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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SERCaMP: a carboxy-terminal protein modification that enables monitoring of ER calcium homeostasis.
Mol. Biol. Cell 25(18) , 2828-39, (2014) Endoplasmic reticulum (ER) calcium homeostasis is disrupted in diverse pathologies, including neurodegeneration, cardiovascular diseases, and diabetes. Temporally defining calcium dysregulation during disease progression, however, has been challenging. Here w... |
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COX-2- and endoplasmic reticulum stress-independent induction of ULBP-1 and enhancement of sensitivity to NK cell-mediated cytotoxicity by celecoxib in colon cancer cells.
Exp. Cell Res. 330(2) , 451-9, (2014) In the present study, we investigated whether celecoxib could induce the expression of NKG2D ligands in clonogenic colon cancer cells, and increase their susceptibility to NK cell-mediated cell death. Celecoxib and its non-coxib analog, 2,5-dimethyl celecoxib... |
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Celecoxib exerts antitumor effects in canine mammary tumor cells via COX‑2‑independent mechanisms.
Int. J. Oncol. 46(3) , 1393-404, (2015) Celecoxib plays antitumor roles via multiple mechanisms in a variety of human cancers. The aim of this study was to clarify the mechanism of action of celecoxib in canine mammary tumors. We examined the antitumor effects of celecoxib in AZACB canine mammary t... |