4-Fluorobenzyl bromide

Names

[ CAS No. ]:
459-46-1

[ Name ]:
4-Fluorobenzyl bromide

[Synonym ]:
FR D1E
EINECS 207-291-5
MFCD00000359
1-(Bromomethyl)-4-fluorobenzene
p-Fluorobenzyl bromide
4-Fluorobenzyl bromide
Benzene, 1-(bromomethyl)-4-fluoro-

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
195.9±15.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₆BrF

[ Molecular Weight ]:
189.025

[ Flash Point ]:
74.8±15.3 °C

[ Exact Mass ]:
187.963684

[ LogP ]:
2.97

[ Vapour Pressure ]:
0.6±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.544

MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34;R36

[ Safety Phrases ]:
S26-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2903999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Fluorobenzyl Alcohol
4-Fluorotoluene
4-Fluorobenzaldehyde
4-(Bromomethyl)phenylboronic acid
p-Toluidine
4-Fluorobenzyl chloride
p-fluorobenzyl ion
(2-Bromoethyl)benzene
Cyanogen bromide
(4-chloro-benzyl)-(4-fluoro-benzyl)-methyl-amine

DownStream

2-bromo-1-[(4-fluorophenyl)methyl]benzimidazole
2-(4-Fluorophenyl)-1-phenylethanone
BENZYL-(4-FLUOROBENZYL)AMINE
4-((4-Fluorobenzyl)oxy)benzaldehyde
N-Methyl-4-fluorobenzylamine
4-Fluorophenylacetic acid
4-Fluorophenylacetyl chloride
4-Fluorobenzyl Alcohol
4-Fluorobenzoic acid
AM0210000 [RTECS]

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

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J. Med. Chem. 51(24) , 8057-67, (2008)

Imaging of programmed cell death (apoptosis) is important in the assessment of therapeutic response in oncology and for diagnosis in cardiac and neurodegenerative disorders. The executioner caspases 3...

2-iodo-4-fluorobenzyl bromide
2-cyano-4-fluorobenzyl bromide
2-cyano-4-fluorobenzyl bromide
3-bromo-4-fluorobenzyl bromide
2-bromo-4-fluorobenzyl bromide
3-Bromo-4-fluorobenzyl bromide
Methyl({thieno[2,3-c]pyridin-2-yl}methyl)amine
4,5,7-trichloro-2,3-dihydro-1H-indole
5-chloro-7-(trifluoromethyl)-2,3-dihydro-1H-indole
N-({thieno[2,3-c]pyridin-2-yl}methyl)cyclopropanamine
2-amino-N-cyclohexyl-N-methylacetamide
N-(2-(3-(4-ethoxyphenyl)-6-oxopyridazin-1(6H)-yl)ethyl)-3,4-difluorobenzamide
2-(Chloromethyl)-5-(4-methoxyphenyl)thiazole
(E)-1-(3-Benzylidene-2-oxoindolin-5-yl)-3-(4-chlorophenyl)urea
1-[(5-chloro-1-methyl-1H-imidazol-2-yl)methyl]-1H-indole-2-carboxylic acid
1-(Cyclopropylmethyl)-3-(2-iodophenyl)urea

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