4-Fluoro-N-methylaniline

[ Density]:
1.1057

[ Boiling Point ]:
79-80ºC(10 torr)

[ Melting Point ]:
79-80°C

[ Molecular Formula ]:
C₇H₈FN

[ Molecular Weight ]:
125.14400

[ Flash Point ]:
75ºC

[ Exact Mass ]:
125.06400

[ PSA ]:
12.03000

[ LogP ]:
1.94040

[ Vapour Pressure ]:
0.853mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.5320(lit.)

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[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H317-H318-H335

[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
UN 2810 6

[ WGK Germany ]:
2

[ HS Code ]:
2921420090

Click to get detail synthetic route

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Role of cytochromes P-450 and flavin-containing monooxygenase in the biotransformation of 4-fluoro-N-methylaniline.

Drug Metab. Dispos. 21(2) , 218-30, (1993)

In vivo and in vitro biotransformation of secondary aromatic amines was investigated using 4-fluoro-N-methylaniline as the model compound. Attention was focused on the role of cytochromes P-450 and th...

Formation of a quinoneimine intermediate of 4-fluoro-N-methylaniline by FMO1: carbon oxidation plus defluorination.

Chem. Res. Toxicol. 23(5) , 861-3, (2010)

Here, we report on the mechanism by which flavin-containing monooxygenase 1 (FMO1) mediates the formation of a reactive intermediate of 4-fluoro-N-methylaniline. FMO1 catalyzed a carbon oxidation reac...

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