1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane

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Names

[ CAS No. ]:
470-67-7

[ Name ]:
1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane

[Synonym ]:
1-Isopropyl-4-methyl-7-oxabicyclo[2.2.1]heptane
Isocineole
1,4-Cineole (natural)
MFCD00209502
1-isopropyl-4-methyl-7-oxa-bicyclo[2.2.1]heptane
1-(2-methylethyl)-4-methyl-7-oxabicyclo[2.2.1]heptane
1,4-EPOXY-P-MENTHANE
1-methyl-4-(propan-2-yl)-7-oxabicyclo[2.2.1]heptane
7-Oxabicyclo[2.2.1]heptane, 1-methyl-4-(1-methylethyl)-
1,4-Cineol
1,4-Cineole
FEMA No. 3658
p-Menthane,1,4-epoxy
EINECS 207-428-9
p-Menthane, 1,4-epoxy

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
173.5±8.0 °C at 760 mmHg

[ Melting Point ]:
−46 °C(lit.)

[ Molecular Formula ]:
C10H18O

[ Molecular Weight ]:
154.249

[ Flash Point ]:
50.7±15.3 °C

[ Exact Mass ]:
154.135757

[ PSA ]:
9.23000

[ LogP ]:
2.58

[ Vapour Pressure ]:
1.7±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.491

[ Storage condition ]:
-20℃

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OS9274000
CHEMICAL NAME :
p-Menthane, 1,4-epoxy-
CAS REGISTRY NUMBER :
470-67-7
BEILSTEIN REFERENCE NO. :
0104974
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H18-O

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,291,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 26,291,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2327 No. of Facilities: 2350 (estimated) No. of Industries: 29 No. of Occupations: 26 No. of Employees: 38044 (estimated) No. of Female Employees: 9165 (estimated)

Safety Information

[ Symbol ]:

GHS02

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226

[ Precautionary Statements ]:
P210-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Risk Phrases ]:
R10

[ Safety Phrases ]:
S16

[ RIDADR ]:
UN 1993 3/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
OS9274000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

Synthetic Route

Precursor & DownStream

Precursor

  • alpha-Terpinene
  • Cineole
  • Terpinine-4-ol
  • Ascaridole
  • isoprene
  • (Z)-terpin
  • Sulfuric acid
  • Terpineol
  • Phosphoric acid

DownStream

  • Terpinine-4-ol

Articles

Inhibition by menthol and its related chemicals of compound action potentials in frog sciatic nerves.

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1,8-cineole, a TRPM8 agonist, is a novel natural antagonist of human TRPA1.

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[Analysis of the chemical constituents of essential oil from Chimonanthus zhejiangensis by GC-MS].

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To analyze the chemical constituents of the essential oil from Chimonanthus zhejiangensis.Steam distillation was employed to extract volatile compounds of essential oil from Chimonanthus zhejiangensis...


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Related Compounds

  • 7-Oxabicyclo[2.2.1]heptan-2-ol,4-methyl-1-(1-methylethyl)-,(1R,2S,4R)-rel-(9CI)
  • Ethanone, 1-(4-methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl)-, exo- (9CI)
  • Ethanone, 1-(4-methyl-7-oxabicyclo[2.2.1]hept-5-en-2-yl)-, endo- (9CI)
  • 4-isopropyl-1-methyl-7-thiabicyclo[2.2.1]heptane
  • 2-Oxabicyclo[2.2.1]heptane,4-methyl-1-(1-methylethyl)-(9CI)
  • 4-methyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
  • (1-(cyclopropylmethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
  • (1-isobutyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
  • (1-(2-fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
  • (1-(prop-2-yn-1-yl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)methanamine
  • 2-(5-(azidomethyl)-1-methyl-1H-pyrazol-3-yl)pyrazine
  • 2-(1-methyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)acetonitrile
  • 2-(1-isopropyl-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)acetonitrile
  • 2-(1-(2-fluoroethyl)-3-(pyrazin-2-yl)-1H-pyrazol-5-yl)acetonitrile
  • {[1-(2,2-difluoroethyl)-5-methyl-1H-pyrazol-4-yl]methyl}[(4-methoxyphenyl)methyl]amine
  • 1H-Pyrazole-4-methanamine, 1-(2,2-difluoroethyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-5-methyl-