N-Phthaloylglycine
Suppliers
Names
[ CAS No. ]:
4702-13-0
[ Name ]:
N-Phthaloylglycine
[Synonym ]:
PHTHALYL GLYCINE
Phthalimidoacetic acid
N-Phthaloylglycine
n-phthalylglycin
2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-
N-phtaloyl glycine
1,3-Dioxo-2-isoindolineacetic acid
2-phthalimidoacetic acid
PHT-GLY-OH
PHTHALOYLGLYCINE
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid
Phthaloglycine
N-PHTHALOGLYCINE
N-Phthalimidoacetic Acid
MFCD00005900
1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
phthalimidomethylcarboxylic acid
EINECS 225-177-3
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
412.6±28.0 °C at 760 mmHg
[ Melting Point ]:
193-196 °C(lit.)
[ Molecular Formula ]:
C10H7NO4
[ Molecular Weight ]:
205.167
[ Flash Point ]:
203.3±24.0 °C
[ Exact Mass ]:
205.037506
[ PSA ]:
74.68000
[ LogP ]:
1.19
[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C
[ Index of Refraction ]:
1.640
[ Storage condition ]:
0-6°C
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NR3439000
- CHEMICAL NAME :
- 2-Isoindolineacetic acid, 1,3-dioxo-
- CAS REGISTRY NUMBER :
- 4702-13-0
- BEILSTEIN REFERENCE NO. :
- 0184174
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C10-H7-N-O4
- MOLECULAR WEIGHT :
- 205.18
- WISWESSER LINE NOTATION :
- T56 BVNVJ C1VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- female 9 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 28,680,1973
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S22-S24/25-S36/37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NR3439000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Acta. Pharm. 58(2) , 231-6, (2008)
The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal ap...
Pharm. Res. 11(10) , 1429-34, (1994)
Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of ...
J. Photochem. Photobiol. B, Biol. 117 , 228-39, (2012)
Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their b...