N-Phthaloylglycine

Modify Date: 2024-01-04 13:14:51

N-Phthaloylglycine Structure
N-Phthaloylglycine structure
Common Name N-Phthaloylglycine
CAS Number 4702-13-0 Molecular Weight 205.167
Density 1.5±0.1 g/cm3 Boiling Point 412.6±28.0 °C at 760 mmHg
Molecular Formula C10H7NO4 Melting Point 193-196 °C(lit.)
MSDS Chinese USA Flash Point 203.3±24.0 °C

 Names

Name N-Phthaloylglycine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 412.6±28.0 °C at 760 mmHg
Melting Point 193-196 °C(lit.)
Molecular Formula C10H7NO4
Molecular Weight 205.167
Flash Point 203.3±24.0 °C
Exact Mass 205.037506
PSA 74.68000
LogP 1.19
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.640
Storage condition 0-6°C
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NR3439000
CHEMICAL NAME :
2-Isoindolineacetic acid, 1,3-dioxo-
CAS REGISTRY NUMBER :
4702-13-0
BEILSTEIN REFERENCE NO. :
0184174
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H7-N-O4
MOLECULAR WEIGHT :
205.18
WISWESSER LINE NOTATION :
T56 BVNVJ C1VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
200 mg/kg
SEX/DURATION :
female 9 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
REFERENCE :
PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 28,680,1973

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R22;R36/37/38
Safety Phrases S22-S24/25-S36/37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NR3439000

 Synthetic Route

 Articles3

More Articles
N-phthaloyl-glycine-hydroxamic acid as serum iron chelator in rats.

Acta. Pharm. 58(2) , 231-6, (2008)

The aim of this study was to investigate the activity of N-phthaloyl-glycine-hydroxamic acid (Phth-Gly-HA) as a new iron chelator in vivo to be used in iron overload diseases. After intraperitoneal ap...

Comparative pharmacokinetic and pharmacodynamic analysis of phthaloyl glycine derivatives with potential antiepileptic activity.

Pharm. Res. 11(10) , 1429-34, (1994)

Glycine, in addition to GABA, is one of the most important neurotransmitter amino acids. The described structure pharmacokinetic pharmacodynamic relationships (SPPR) study explored the possibility of ...

Synthesis, crystal structure, DNA binding and in vitro biological studies of Ni(II), Cu(II) and Zn(II) complexes of N-phthaloylglycine.

J. Photochem. Photobiol. B, Biol. 117 , 228-39, (2012)

Ni(II), Cu(II) and Zn(II) metal complexes of N-phthaloylglycine were synthesized, characterized, reported for single crystal X-ray diffraction analysis for Ni(II) complex, and investigated for their b...

 Synonyms

PHTHALYL GLYCINE
Phthalimidoacetic acid
N-Phthaloylglycine
n-phthalylglycin
2H-Isoindole-2-acetic acid, 1,3-dihydro-1,3-dioxo-
N-phtaloyl glycine
1,3-Dioxo-2-isoindolineacetic acid
2-phthalimidoacetic acid
PHT-GLY-OH
PHTHALOYLGLYCINE
(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)acetic acid
Phthaloglycine
N-PHTHALOGLYCINE
N-Phthalimidoacetic Acid
MFCD00005900
1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid
phthalimidomethylcarboxylic acid
EINECS 225-177-3