(-)-Lycorine
Suppliers
Names
[ CAS No. ]:
476-28-8
[ Name ]:
(-)-Lycorine
[Synonym ]:
3,3a-Didehydrolycoran-1a,2b-diol
Amarylline
(1a,2b)-3,12-Didehydro-9,10-[methylenebis(oxy)]galanthan-1,2-diol
(1S,2S,12bS,12cS)-2,4,5,7,12b,12c-Hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol
1H-[1,3]Dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 2,4,5,7,12b,12c-hexahydro-, (1S,2S,12bS,12cS)-
Lycorine
(1S,2S,12bS,12cS)-1,2-diol-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine
Galanthidine
Belamarine
Licorine
Narcissine
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
477.4±45.0 °C at 760 mmHg
[ Melting Point ]:
253-255ºC (dec.)
[ Molecular Formula ]:
C16H17NO4
[ Molecular Weight ]:
287.310
[ Flash Point ]:
242.5±28.7 °C
[ Exact Mass ]:
287.115753
[ PSA ]:
62.16000
[ LogP ]:
0.77
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.733
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OL2900000
- CHEMICAL NAME :
- Lycoran-1-alpha,2-beta-diol, 3,3-alpha-didehydro-
- CAS REGISTRY NUMBER :
- 476-28-8
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C16-H17-N-O4
- MOLECULAR WEIGHT :
- 287.34
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 10700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 56(1),23S,1960
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 145 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - rigidity (including catalepsy) Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 56(1),23S,1960
Safety Information
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
R25
[ Safety Phrases ]:
45
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ Hazard Class ]:
9.0