Gabapentin enacarbil

Suppliers

Names

[ Name ]:
Gabapentin enacarbil

[Synonym ]:
{[(1-isobutanoyloxyethoxy)carbonyl]aminomethyl}-1-cyclohexaneacetic acid
{1-[({[1-(Isobutyryloxy)ethoxy]carbonyl}amino)methyl]cyclohexyl}acetic acid
Solzira
Cyclohexaneacetic acid, 1-[[[[1-(2-methyl-1-oxopropoxy)ethoxy]carbonyl]amino]methyl]-
UNII-75OCL1SPBQ
UNII:75OCL1SPBQ
Horizant
2-[1-[[1-(2-methylpropanoyloxy)ethoxycarbonylamino]methyl]cyclohexyl]acetic acid
ASP-8825
Gabapentin enacarbil
Xenoport

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
482.0±20.0 °C at 760 mmHg

[ Melting Point ]:
65ºC

[ Molecular Formula ]:
C₁₆H₂₇NO₆

[ Molecular Weight ]:
329.389

[ Flash Point ]:
245.3±21.8 °C

[ Exact Mass ]:
329.183838

[ PSA ]:
101.93000

[ LogP ]:
3.07

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.481

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Propanoic acid, 2-Methyl-, 1-[[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]oxy]ethyl ester
Gabapentin
1-[(chlorocarbonyl)oxy]ethyl 2-methylpropionate
1-(((4-NITROPHENOXY)CARBONYL)OXY)ETHYL ISOBUTYRATE
1-{[(α-chloroethoxy)carbonyl]aminomethyl}-1-cyclohexane acetic acid
Isobutyric acid
1-(aminomethyl)cyclohexaneacetic acid tetrabutylammonium salt
O-1-(isobutyryloxy)ethyl S-dodecylcarbonothioate
trimethylsilyl 2-(1-((((1-chloroethoxy)carbonyl)amino)methyl)cyclohexyl)acetate