Afzelin

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Names

[ CAS No. ]:
482-39-3

[ Name ]:
Afzelin

[Synonym ]:
kaempferol 3-O-α-L-rhamnopyranoside
kaempferol-3-rhamnoside
5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-α-L-mannopyranoside
5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one
4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
Kaempferol-3-O-α-L-rhamnoside
Kaempferol 3-O-Alpha-L-Rhamnoside
Afzelin
Trihydroxy-SL0101
4H-1-Benzopyran-4-one, 3-((6-deoxy-α-L-mannopyranosyl)oxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-
Kaempferol 3-rhamnoside
3-O-α-rhamnosylkaempferol
Kaempferin

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
765.6±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H20O10

[ Molecular Weight ]:
432.378

[ Flash Point ]:
272.4±26.4 °C

[ Exact Mass ]:
432.105652

[ PSA ]:
170.05000

[ LogP ]:
2.37

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.748

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbonic acid, (2S,6S)-5,6-dihydro-6-methyl-5-oxo-2H-pyran-2-yl 1,1-dimethylethyl ester
  • 5,7-BIS-(BENZYLOXY)-2-(4-(BENZYLOXY)PHENYL)-3-HYDROXY-4H-CHROMEN-4-ONE
  • 1-(Furan-2-yl)ethanone
  • 5,7-BIS-(BENZYLOXY)-2-(4-(BENZYLOXY)PHENYL)-4H-CHROMEN-4-ONE
  • Naringenin
  • (S)-6-hydroxy-2-methyl-2,6-dihydropyran-3-one

DownStream

  • Kaempferol
  • Alpha-L-Rhamnopyranose

Articles

Antibacterial effects of afzelin isolated from Cornus macrophylla on Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals.

Molecules 19(3) , 3173-80, (2014)

The crude ethyl acetate extract of the leaves of Cornus macrophylla showed antibacterial activity against Pseudomonas aeruginosa, a leading cause of illness in immunocompromised individuals. Bioactivi...

Antagonizing effects and mechanisms of afzelin against UVB-induced cell damage.

PLoS ONE 8(4) , e61971, (2013)

Ultraviolet (UV) radiation induces DNA damage, oxidative stress, and inflammatory processes in human keratinocytes, resulting in skin inflammation, photoaging, and photocarcinogenesis. Adequate protec...


More Articles

Related Compounds

  • afzelin
  • 2",4"-Di-O-(E-p-coumaroyl)afzelin
  • 2",4"-Di-O-(Z-p-coumaroyl)afzelin
  • N1-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)-N2-(p-tolyl)oxalamide
  • N1-(3-chlorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(2-fluorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(2,4-difluorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(4-fluorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(3-fluorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(4-ethylphenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(2,3-dimethylphenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
  • N1-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)-N2-(2-methoxyphenyl)oxalamide
  • N1-(2-chlorophenyl)-N2-(2-(indolin-1-yl)-2-(thiophen-2-yl)ethyl)oxalamide
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