Curcumol

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Names

[ Name ]:
Curcumol

[Synonym ]:
6H-3a,6-Epoxyazulen-6-ol, octahydro-3-methyl-8-methylene-5-(1-methylethyl)-, (3S,3aS,5S,8aS)-
(3S,3aS,5S,8aS)-3-methyl-8-methylidene-5-(propan-2-yl)octahydro-6H-3a,6-epoxyazulen-6-ol
(3S,3aS,5S,6R,8aS)-Octahydro-3-methyl-8-methylene-5-(1-methylethyl)-6H-3a,6-epoxyazulen-6-ol
(1S,2S,5S,9S)-9-Isopropyl-2-methyl-6-methylene-11-oxatricyclo[6.2.1.0]undecan-8-ol

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
334.5±42.0 °C at 760 mmHg

[ Melting Point ]:
141-142ºC

[ Molecular Formula ]:
C₁₅H₂₄O₂

[ Molecular Weight ]:
236.350

[ Flash Point ]:
134.7±22.1 °C

[ Exact Mass ]:
236.177628

[ PSA ]:
29.46000

[ LogP ]:
3.25

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.526

Safety Information

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29321900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Isolation and identification of phase 1 metabolites of curcumol in rats.

Drug Metab. Dispos. 38(11) , 2014-22, (2010)

Curcumol is one of the major components of the essential oil of Curcuma wenyujin with the structure of a guaiane-type sesquiterpenoid hemiketal. It exhibits clear antitumor, antihepatic fibrosis, anti...

Subunit-specific inhibition of glycine receptors by curcumol.

J. Pharmacol. Exp. Ther. 343(2) , 371-9, (2012)

Emerging evidence has suggested that inhibitory glycine receptors (GlyRs) are an important molecular target in the treatment of numerous neurological disorders. Rhizoma curcumae is a medicinal plant w...

Chemical constituents from the radix of Curcuma wenyujin.

Fitoterapia 80(6) , 374-6, (2009)

Phytochemical study on the ethanol extract of the radixes of Curcuma wenyujin Y. H. Chen et C. Ling led to the isolation of three new compounds curcuminol F (1) curcuminol G (2) and wenyujinoside (3) ...

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