Amiphenazole

Names

[ CAS No. ]:
490-55-1

[ Name ]:
Amiphenazole

[Synonym ]:
5-phenyl-thiazole-2,4-diyldiamine
Fenamizol
Dizol
Phenamizol
2,4-diamino-5-phenylthiazole
Amiphenazole
Daptazile
5-phenyl-thiazole-2,4-diamine
Amifenazol
Phenamizole
Amiphenazol
Daftazol
5-Phenyl-thiazol-2,4-diyldiamin

Chemical & Physical Properties

[ Density]:
1.347g/cm3

[ Boiling Point ]:
413.3ºC at 760mmHg

[ Molecular Formula ]:
C9H9N3S

[ Molecular Weight ]:
191.25300

[ Flash Point ]:
203.7ºC

[ Exact Mass ]:
191.05200

[ PSA ]:
93.17000

[ LogP ]:
3.13690

[ Vapour Pressure ]:
4.86E-07mmHg at 25°C

[ Index of Refraction ]:
1.715

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ4020000
CHEMICAL NAME :
Thiazole, 2,4-diamino-5-phenyl-
CAS REGISTRY NUMBER :
490-55-1
BEILSTEIN REFERENCE NO. :
0157088
LAST UPDATED :
199706
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-N3-S
MOLECULAR WEIGHT :
191.27
WISWESSER LINE NOTATION :
T5N CSJ BZ DR& EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
290 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,489,1973

Safety Information

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzeneacetonitrile,a-[(phenylsulfonyl)oxy]-
  • Bromobenzyl cyanide
  • Sodium cyanide
  • Benzaldehyde

DownStream

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Related Compounds

  • N-[4-(3-fluorophenyl)piperidin-3-yl]-1-methylcyclopropane-1-carboxamide
  • 2-Amino-3-[1-(2-bromoacetyl)piperidin-4-yl]propanoic acid
  • tert-butyl N-[3-(methylamino)bicyclo[1.1.1]pentan-1-yl]carbamate
  • sodium 2-[5-({[(tert-butoxy)carbonyl]amino}methyl)-4H-1,2,4-triazol-3-yl]acetate
  • (2S)-2-amino-3-[(3S)-2-oxopyrrolidin-3-yl]propanoic acid, trifluoroacetic acid
  • 3-amino-1H-pyrazolo[3,4-c]pyridine-4-carboxylic acid hydrochloride
  • 5-Oxaspiro[bicyclo[4.2.0]octane-7,1'-cyclopentane]-8-one
  • (2-Methylbutyl)(3-methylpent-1-yn-3-yl)amine
  • (3,3-Dimethylbutyl)(3-methylpent-1-yn-3-yl)amine
  • 1-(4-Fluorophenyl)-3-(prop-2-en-1-ylsulfanyl)propan-1-one