Amiphenazole
Names
[ CAS No. ]:
490-55-1
[ Name ]:
Amiphenazole
[Synonym ]:
5-phenyl-thiazole-2,4-diyldiamine
Fenamizol
Dizol
Phenamizol
2,4-diamino-5-phenylthiazole
Amiphenazole
Daptazile
5-phenyl-thiazole-2,4-diamine
Amifenazol
Phenamizole
Amiphenazol
Daftazol
5-Phenyl-thiazol-2,4-diyldiamin
Chemical & Physical Properties
[ Density]:
1.347g/cm3
[ Boiling Point ]:
413.3ºC at 760mmHg
[ Molecular Formula ]:
C9H9N3S
[ Molecular Weight ]:
191.25300
[ Flash Point ]:
203.7ºC
[ Exact Mass ]:
191.05200
[ PSA ]:
93.17000
[ LogP ]:
3.13690
[ Vapour Pressure ]:
4.86E-07mmHg at 25°C
[ Index of Refraction ]:
1.715
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ4020000
- CHEMICAL NAME :
- Thiazole, 2,4-diamino-5-phenyl-
- CAS REGISTRY NUMBER :
- 490-55-1
- BEILSTEIN REFERENCE NO. :
- 0157088
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H9-N3-S
- MOLECULAR WEIGHT :
- 191.27
- WISWESSER LINE NOTATION :
- T5N CSJ BZ DR& EZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,1125,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 290 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory obstruction Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 7,489,1973
Safety Information
[ HS Code ]:
2934100090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%