2,5-Dihydroxyacetophenone

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Names

[ CAS No. ]:
490-78-8

[ Name ]:
2,5-Dihydroxyacetophenone

[Synonym ]:
Ethanone, 1- (2,5-dihydroxyphenyl)-
2,5-Dihydroxyphenyl methyl ketone,2-Acetyl-1,4-dihydroxybenzene,2-Acetylhydroquinone
2’,5’-Dihydroxyacetophenone
1-(2,5-Dihydroxyphenyl)ethanone
2',5'-Dihydroxyacetophenone
2',5'-Dihydroxy acetophenone
Quinacetophenone
EINECS 207-716-4
2-Acetylhydroquinone
2‘,5‘-Dihydroxyacetophenone
Ethanone, 1-(2,5-dihydroxyphenyl)-
MFCD00002343

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
329.2±27.0 °C at 760 mmHg

[ Melting Point ]:
204-206 °C(lit.)

[ Molecular Formula ]:
C8H8O3

[ Molecular Weight ]:
152.147

[ Flash Point ]:
167.1±20.2 °C

[ Exact Mass ]:
152.047348

[ PSA ]:
57.53000

[ LogP ]:
1.59

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM7700000
CHEMICAL NAME :
Acetophenone, 2',5'-dihydroxy-
CAS REGISTRY NUMBER :
490-78-8
BEILSTEIN REFERENCE NO. :
0637903
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-O3
MOLECULAR WEIGHT :
152.16
WISWESSER LINE NOTATION :
QR CQ BV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 5,140,1953

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AM7700000

[ HS Code ]:
29145000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • p-Diacetoxybenzene
  • 1-(2,5-Dimethoxyphenyl)ethanone
  • acetic acid
  • Hydroquinone
  • Pyruvic acid
  • 1,4-Benzoquinone
  • 4-Acetoxyphenol
  • 2-Acetylcyclohexanone
  • Acetyl chloride
  • 2-Acetyl-1,4-benzoquinone

DownStream

  • phenyl-bis[3-(6-hydroxy)flavanonyl]methane
  • 6-hydroxyflavanone
  • 3-benzylidene-2-phenyl-6-hydroxy-2,3-dihydro-4H-1-benzopyran-4-one
  • 1,2,4-Trihydroxybenzene
  • Nitrogenistein
  • 1-(2,5-dihydroxyphenyl)but-2-en-1-one
  • 3-Formyl-6-methoxychromone
  • 3-(4-chlorophenyl)-1-(2,5-dihydroxyphenyl)prop-2-en-1-one
  • 1-(2,5-dihydroxyphenyl)-3-phenylprop-2-en-1-one

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

2,5-Dihydroxyacetophenone: a matrix for highly sensitive matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of proteins using manual and automated preparation techniques Wenzel, Thomas; Sparbier, Katrin; Mieruch, Thorsten; Kostrzewa, Markus

Rapid Commun. Mass Spectrom. 20 , 785-789, (2005)


More Articles

Related Compounds

  • 2,5-dihydroxyacetophenone
  • 2,5-dihydroxy-3,6-dinitro-cyclohexa-2,5-diene-1,4-dione
  • 2,5-dihydroxy-4-octadecylbenzoic acid
  • 2,5-dihydroxy-3-methyl-6-nonadecylcyclohexa-2,5-diene-1,4-dione
  • 2,5-dihydroxy-2-methyltridecan-3-one
  • 2,5-dihydroxy-2,3-dihydrobenzo[b]furan
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • rac-1-[(1R,5S)-5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohex-3-ene-1-carbonyl]pyrrolidine-3-carboxylic acid
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide