Fluoroacetonitrile

Suppliers

Names

[ CAS No. ]:
503-20-8

[ Name ]:
Fluoroacetonitrile

[Synonym ]:
Acetonitrile, 2-fluoro-
MFCD00009969
Fluoroacetonitrile
2-fluoroacetonitrile

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
79.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-13 °C

[ Molecular Formula ]:
C2H2FN

[ Molecular Weight ]:
59.042

[ Flash Point ]:
-13.9±0.0 °C

[ Exact Mass ]:
59.017128

[ PSA ]:
23.79000

[ LogP ]:
-0.39

[ Vapour Pressure ]:
88.8±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.303

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AM0175000
CHEMICAL NAME :
Acetonitrile, fluoro-
CAS REGISTRY NUMBER :
503-20-8
BEILSTEIN REFERENCE NO. :
1697891
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C2-H2-F-N
MOLECULAR WEIGHT :
59.05
WISWESSER LINE NOTATION :
NC1F

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 78,3484,1956
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311 + H331-H315-H319-H335

[ Precautionary Statements ]:
P210-P261-P280-P301 + P310-P305 + P351 + P338-P311

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;T:Toxic;

[ Risk Phrases ]:
R11;R23/24/25;R36/37/38

[ Safety Phrases ]:
S16-S26-S27-S36/37/39-S45

[ RIDADR ]:
UN 3273

[ RTECS ]:
AM0175000

[ Packaging Group ]:
II

[ Hazard Class ]:
3.1

[ HS Code ]:
2926909090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Fluoroacetamide
  • 2-chloroacetonitrile
  • Acetonitrile
  • Cyanomethyl p-toluenesulfonate

DownStream

  • N-butyl fluoroacetate
  • 2-(fluoromethyl)-1H-quinazolin-4-one
  • Fluoroacetamide
  • Fluoroacetic acid propyl ester
  • 2'-fluoroacetophenone
  • Fluoroacetic acid 2-ethylhexyl ester
  • fluoroacetic acid
  • 1-fluoro-3-phenylpropan-2-amine
  • Ethanone, 1-cyclohexyl-2-fluoro- (9CI)
  • 2-amino-2-(fluoromethyl)pent-3-enenitrile

Customs

[ HS Code ]: 2926909090

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

2-Fluoromethyl-4, 4, 6-trimetiiyl-1, 3-oxasine as a new reagent for the preparation of a-fluoroaldehydes. Patrick TB, et al.

Tetrahedron Lett. 31(2) , 179-82, (1990)

Preparative flow techniques. 2. Grignard addition reaction on fluoroaceto-nitrile: Synthesis of 2-amino-2-fluoromethyl-3-pentenenitrile. Gerhart F, et al.

J. Fluor. Chem. 50(2) , 243-49, (1990)


More Articles

Related Compounds

  • fluoroacetonitrile
  • 4-Fluoroacetonitrile
  • BROMOFLUOROACETONITRILE
  • chlorofluoroacetonitrile
  • Dibromo fluoroacetonitrile
  • dichlorofluoroacetonitrile
  • N-(6-Oxabicyclo[3.1.0]hexan-2-YL)-N-(2-hydroxyethyl)-2-nitrobenzenesulfonamide
  • Methyl 5-chloro-2-ethylimidazo[1,2-A]pyridine-3-carboxylate
  • [Amino-[5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl]methyl] formate
  • Benzyl 4-(6-chloro-5-methoxypyrimidin-4-YL)piperazine-1-carboxylate
  • Ethyl 5-chloro-6-morpholinonicotinate
  • Tert-butyl 2-(2-methylpyrimidin-5-YL)morpholine-4-carboxylate
  • Benzyl 4-cyano-4-((4-(methoxycarbonyl)phenyl)amino)piperidine-1-carboxylate
  • [1-Amino-2-(4-bromo-3-fluorophenyl)ethyl] formate
  • (S)-Tert-butyl (1-(4-fluorophenyl)-2-hydroxy-2-methylpropyl)carbamate
  • 4-Chloro-5-iodo-N,N-bis(4-methoxybenzyl)pyridin-2-amine
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.