Arachidonic acid
Suppliers
Names
[ CAS No. ]:
506-32-1
[ Name ]:
Arachidonic acid
[Synonym ]:
(5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid
AA
Immunocytophyte
eicosatetraenoic acid
MFCD00004417
PUFA 20:4n-6
ARACHIDONIC ACID(RG)
5,8,11,14-Icosatetraenoic Acid
Arachidonic acid
Hydrazinecarboselenoamide
ARA
5,8,11,14-Eicosatetraenoic Acid
(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid
C20:4 (cis-5,8,11,14)
20:4n-6
5,8,11,14-all-cis-Eicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, (all-Z)-
5,8,11,14-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-
Arachidonate
(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid
Arachidonic
EINECS 208-033-4
(all-Z)-5,8,11,14-Eicosatetraenoic acid
Chemical & Physical Properties
[ Density]:
0.9±0.1 g/cm3
[ Boiling Point ]:
407.5±0.0 °C at 760 mmHg
[ Melting Point ]:
−49 °C(lit.)
[ Molecular Formula ]:
C20H32O2
[ Molecular Weight ]:
304.467
[ Flash Point ]:
336.3±18.0 °C
[ Exact Mass ]:
304.240234
[ PSA ]:
37.30000
[ LogP ]:
6.91
[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C
[ Index of Refraction ]:
1.501
[ Water Solubility ]:
PRACTICALLY INSOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CE6675000
- CHEMICAL NAME :
- Arachidonic acid
- CAS REGISTRY NUMBER :
- 506-32-1
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C20-H32-O2
- MOLECULAR WEIGHT :
- 304.52
- WISWESSER LINE NOTATION :
- QV4U3U3U3U6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 39200 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 80 ug/kg
- SEX/DURATION :
- female 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 320 umol/L
- REFERENCE :
- PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,95,1986 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,481,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1132 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 79 (estimated) No. of Female Employees: 60 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
F
[ Risk Phrases ]:
R19
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CE6675000
[ Packaging Group ]:
I; II; III
[ Hazard Class ]:
6.1
[ HS Code ]:
2916190090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916190090
[ Summary ]:
2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%
Articles
J. Nutr. Biochem. 25(12) , 1254-62, (2014)
The n-3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been shown to enhance the effect of chemotherapeutic drugs in clinical studies in cancer patients an...
J. Nutr. 145(3) , 654-60, (2015)
Fingertip prick whole blood collection on chromatography paper is amenable to high-throughput fatty acid (FA) profiling for large clinical and field studies. However, sample storage is problematic bec...
Clin. Exp. Allergy 44(12) , 1515-24, (2014)
Atopic dermatitis is an inflammatory skin disease that is characterized by a reduced skin barrier function, reduced filaggrin (FLG) expression as well as increased colonization by Staphylococcus aureu...