4-Fluoro-L-phenylalanine

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Names

[ CAS No. ]:
51-65-0

[ Name ]:
4-Fluoro-L-phenylalanine

[Synonym ]:
EINECS 200-113-7
p-Fluoro-DL-phenylalanine
S-(-)-p-Fluorophenylalanine
para-fluorophenylalanine
4-Fluorophenylalanine
DL-4-Fluorophenylalanine
4-Fluoro-DL-.β.-phenylalanine
L-4-Fluorophenylalanine
p-Fluoro-L-phenylalanine
L-4-Fluoro-Phenylalanine
(2S)-2-amino-3-(4-fluorophenyl)propanoic acid
2-Amino-3-(4-fluorophenyl)propanoic acid
Phenylalanine, 4-fluoro-
2-Amino-3-(4-fluorophenyl)propionic Acid
H-DL-Phe(4-F)-OH
4-Fluoro-DL-phenylalanine
para-fluoro-l-phenylalanine
MFCD00002600
(S)-2-Amino-3-(4-fluorophenyl)propanoic acid

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
313.3±32.0 °C at 760 mmHg

[ Melting Point ]:
253-255ºC

[ Molecular Formula ]:
C9H10FNO2

[ Molecular Weight ]:
183.180

[ Flash Point ]:
143.3±25.1 °C

[ Exact Mass ]:
183.069550

[ PSA ]:
63.32000

[ LogP ]:
1.16

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.555

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidising agents. May be light sensitive.

[ Water Solubility ]:
slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AY6315000
CHEMICAL NAME :
Alanine, 3-(p-fluorophenyl)-, DL-
CAS REGISTRY NUMBER :
51-65-0
LAST UPDATED :
199701
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C9-H10-F-N-O2
MOLECULAR WEIGHT :
183.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Rodent - rabbit Kidney
DOSE/DURATION :
500 umol/L
REFERENCE :
ECREAL Experimental Cell Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.10- 1950- Volume(issue)/page/year: 36,92,1964

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811

[ WGK Germany ]:
3

[ RTECS ]:
AY6315000

[ Packaging Group ]:
III

[ HS Code ]:
2922499990

Precursor & DownStream

Precursor

  • 5(4H)-Oxazolone,4-[(4-fluorophenyl)methylene]-2-phenyl-
  • diethyl 2-acetamido-2-[(4-fluorophenyl)methyl]propanedioate
  • n-acetyl-4-fluoro-dl-phenylalanine
  • α-benzoylamino-4-fluoro-trans-cinnamic acid ethyl ester
  • 2-benzamido-3-(4-fluorophenyl)prop-2-enoic acid
  • (+/-)-15-aminomethyl-14-hydroxy-5,5-dimethyl-2,8-dithia[9](2,5)pyridophane

DownStream

  • Phenylacetic acid
  • H-D-Phe(4-F)-OH
  • Boc-L-4-Fluorophenylalanine
  • 4-Fluoro-Phe-OH
  • 3-Amino-3-(4-fluorophenyl)propanoic acid
  • 4-Fluorophenethylamine
  • Z-4-Fluoro-Phe-OH
  • Methyl 2-amino-3-(4-fluorophenyl)propanoate hydrochloride
  • 3-(4-fluorophenyl)-2-[(2,2,2-trifluoroacetyl)amino]propanoic acid

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 4-Fluoro-L-phenylalanine
  • N-Boc-4-fluoro-L-phenylalanine
  • N-Boc-4-fluoro-L-phenylalanine
  • N-Fmoc-4-fluoro-L-phenylalanine
  • 2-Chloro-4-fluoro-L-phenylalanine
  • n-acetyl-4-fluoro-l-phenylalanine
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