|p|-Aminophenol hydrochloride

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Names

[ CAS No. ]:
51-78-5

[ Name ]:
|p|-Aminophenol hydrochloride

[Synonym ]:
4-Aminophenol hydrochloride
EINECS 200-122-6
p-Aminophenol hydrochloride
4-Hydroxyaniline hydrochloride
MFCD00012996

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
282ºC at 760mmHg

[ Melting Point ]:
302 °C

[ Molecular Formula ]:
C6H8ClNO

[ Molecular Weight ]:
145.58700

[ Flash Point ]:
124.3ºC

[ Exact Mass ]:
145.02900

[ PSA ]:
46.25000

[ LogP ]:
2.35760

[ Stability ]:
Stable, but hygroscopic, air and light sensitive. Incompatible with strong oxidizing agents.

[ Water Solubility ]:
soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SJ6070000
CHEMICAL NAME :
Phenol, p-amino-, hydrochloride
CAS REGISTRY NUMBER :
51-78-5
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C6-H7-N-O.Cl-H
MOLECULAR WEIGHT :
145.60
WISWESSER LINE NOTATION :
ZR DQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :
Insect - Drosophila melanogaster
DOSE/DURATION :
20 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,87,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1445 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 198 (estimated) No. of Female Employees: 151 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38;R43

[ Safety Phrases ]:
S28-S36

[ RIDADR ]:
2811.0

[ WGK Germany ]:
3

[ RTECS ]:
SJ6070000

[ Packaging Group ]:
I; II; III

[ Hazard Class ]:
6.1

[ HS Code ]:
29222900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Aminophenol
  • Phenol
  • Hydrochloric acid
  • 4-Hydroxy-3-sulfoaniline
  • α-methylsuccinic di-p-anisidine

DownStream

  • Methyl 5-amino-2-hydroxybenzoate
  • 4-Methylaminophenol sulfate
  • tert-Butyl (4-hydroxyphenyl)carbamate
  • [2-methyl-1-[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]propan-2-yl] carbonate
  • (1Z)-1-[(4-hydroxyphenyl)hydrazinylidene]naphthalen-2-one
  • Thiourea,N-(2-hydroxyphenyl)
  • indophenol
  • (4-aminophenyl) N-methylcarbamate
  • phenol blue
  • p-Anisidine

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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