|p|-Aminophenol hydrochloride
|p|-Aminophenol hydrochloride structure
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Common Name | |p|-Aminophenol hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 51-78-5 | Molecular Weight | 145.58700 | |
| Density | 1.21g/cm3 | Boiling Point | 282ºC at 760mmHg | |
| Molecular Formula | C6H8ClNO | Melting Point | 302 °C | |
| MSDS | Chinese USA | Flash Point | 124.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Summary: 4-Aminophenol Hydrochloride, also known as |p|-Aminophenol hydrochloride, has a CAS number of 51-78-5. Its molecular formula is C6H8ClNO and molecular weight is 145.58700. It appears as white to off-white crystalline powder, with a melting point of 302 °C and boiling point of 282ºC, and a density of 1.21g/cm3. This compound is primarily used for mink dyeing, and can also serve as a sulfonated dye or pharmaceutical intermediate. For research-use only, not for medical or clinical usage.
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | 4-Aminophenol Hydrochloride |
|---|---|
| Synonym | More Synonyms |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.21g/cm3 |
|---|---|
| Boiling Point | 282ºC at 760mmHg |
| Melting Point | 302 °C |
| Molecular Formula | C6H8ClNO |
| Molecular Weight | 145.58700 |
| Flash Point | 124.3ºC |
| Exact Mass | 145.02900 |
| PSA | 46.25000 |
| LogP | 2.35760 |
| InChIKey | RVGOBWDGAVAVPJ-UHFFFAOYSA-N |
| SMILES | Cl.Nc1ccc(O)cc1 |
| Stability | Stable, but hygroscopic, air and light sensitive. Incompatible with strong oxidizing agents. |
| Water Solubility | soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H317-H319-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38;R43 |
| Safety Phrases | S28-S36 |
| RIDADR | 2811.0 |
| WGK Germany | 3 |
| RTECS | SJ6070000 |
| Packaging Group | I; II; III |
| Hazard Class | 6.1 |
| HS Code | 29222900 |
This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.
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|p|-Aminophenol... CAS#:51-78-5 |
| Literature: Aksenov; Lyakhovnenko; Kugutov Chemistry of Heterocyclic Compounds, 2011 , vol. 46, # 10 p. 1262 - 1265 |
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|p|-Aminophenol... CAS#:51-78-5 |
| Literature: Aksenov; Lyakhovnenko; Kugutov Chemistry of Heterocyclic Compounds, 2011 , vol. 46, # 10 p. 1262 - 1265 |
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|p|-Aminophenol... CAS#:51-78-5 |
| Literature: Noyes; Clement Chemische Berichte, 1893 , vol. 26, p. 990 |
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Detail
Learn More
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| Literature: Giuffrida; Chimienti Gazzetta Chimica Italiana, 1904 , vol. 34 II, p. 262 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 5 | |
|---|---|
| DownStream 10 | |
CAS#:42753-75-3
CAS#:55-55-0
CAS#:54840-15-2![[2-methyl-1-[4-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]propan-2-yl] carbonate structure](https://image.chemsrc.com/caspic/040/95932-40-4.png)
CAS#:95932-40-4![(1Z)-1-[(4-hydroxyphenyl)hydrazinylidene]naphthalen-2-one structure](https://image.chemsrc.com/caspic/191/14934-27-1.png)
CAS#:14934-27-1
CAS#:1520-26-9
CAS#:500-85-6
CAS#:20120-72-3
CAS#:2150-58-5
CAS#:104-94-9This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2922299090 |
|---|---|
| Summary | 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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Silver nanoparticles-decorated polyphosphazene nanotubes: synthesis and applications.
Nanoscale 5(17) , 7913-9, (2013) Herein, we report the preparation of poly (cyclotriphosphazene-co-4,4'-sulfonyldiphenol) (PZS) nanotubes decorated with Ag nanoparticles (NPs). The PZS nanotubes have been synthesized firstly via an i... |
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Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.
J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas... |
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Amine-functionalized polyglycidyl methacrylate microsphere as a unified template for the synthesis of gold nanoparticles and single-crystal gold plates.
Macromol. Rapid Commun. 34(6) , 504-10, (2013) Polyglycidyl methacrylate (PGMA) microspheres, crosslinked and surface-functionalized by amine, can be used as a solid-state template for the synthesis of gold (Au) crystals in the forms of either nan... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
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Name: Cytotoxicity against human CCRF-CEM cells
Source: ChEMBL
Target: CCRF-CEM
External Id: CHEMBL913936
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Name: Activity against caspase-mediated apoptosis in mouse L1210 cells at 0.1 mM
Source: ChEMBL
Target: L1210
External Id: CHEMBL914537
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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Aminophenol hydrochloride |
| EINECS 200-122-6 |
| p-Aminophenol hydrochloride |
| 4-Hydroxyaniline hydrochloride |
| MFCD00012996 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the SMILES notation of 4-Aminophenol Hydrochloride? |
| A: SMILES notation of 4-Aminophenol Hydrochloride is Cl.Nc1ccc(O)cc1. |
| Q: What is the boiling point of 4-Aminophenol Hydrochloride? |
| A: Boiling point of 4-Aminophenol Hydrochloride is 282ºC at 760mmHg. |
| Q: What are the upstream materials of 4-Aminophenol Hydrochloride? |
| A: Related upstream materials(CAS) of 4-Aminophenol Hydrochloride: 123-30-8;108-95-2;7647-01-0;2835-04-3;78533-09-2. |
| Q: What is the English name of 4-Aminophenol Hydrochloride? |
| A: The English name of 4-Aminophenol Hydrochloride is 4-Aminophenol Hydrochloride. |
| Q: What English synonyms does 4-Aminophenol Hydrochloride have? |
| A: English synonyms of 4-Aminophenol Hydrochloride: 4-Aminophenol hydrochloride, EINECS 200-122-6, p-Aminophenol hydrochloride, 4-Hydroxyaniline hydrochloride, MFCD00012996. |
| Q: What is the safety information for 4-Aminophenol Hydrochloride? |
| A: Safety information for 4-Aminophenol Hydrochloride: S28-S36. |
| Q: What is the LogP of 4-Aminophenol Hydrochloride? |
| A: LogP of 4-Aminophenol Hydrochloride is 2.35760. |
| Q: What is the molecular weight of 4-Aminophenol Hydrochloride? |
| A: Molecular weight of 4-Aminophenol Hydrochloride is 145.58700. |
| Q: What are the downstream products of 4-Aminophenol Hydrochloride? |
| A: Related downstream products(CAS) of 4-Aminophenol Hydrochloride: 42753-75-3;55-55-0;54840-15-2;95932-40-4;14934-27-1;1520-26-9;500-85-6;20120-72-3;2150-58-5;104-94-9. |
| Q: What is the InChIKey of 4-Aminophenol Hydrochloride? |
| A: InChIKey of 4-Aminophenol Hydrochloride is RVGOBWDGAVAVPJ-UHFFFAOYSA-N. |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |