thiophene-3-carboxamide

Names

[ Name ]:
thiophene-3-carboxamide

[Synonym ]:
Thiophen-3-carbonsaeure-amid
thiophene-3-carboxylic acid amide
3-Thiophenecarboxamide
MFCD05664206
3-carbamoylthiophene
F9995-1211
thiophen-3-carboxamide
3-thenamide

Chemical & Physical Properties

[ Density]:
1.302g/cm3

[ Boiling Point ]:
313.5ºC at 760 mmHg

[ Melting Point ]:
181-184ºC(lit.)

[ Molecular Formula ]:
C₅H₅NOS

[ Molecular Weight ]:
127.16400

[ Flash Point ]:
143.4ºC

[ Exact Mass ]:
127.00900

[ PSA ]:
71.33000

[ LogP ]:
1.54730

[ Index of Refraction ]:
1.603

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

iodothiophene
carbon monoxide
3-Thiophenecarbonitrile
3-Bromothiophene
3-Acetylthiophene
3-Thienylacetic acid
3-Thienylmethanol
3-Thiophenecarboxaldehyde
Carbon monooxide-molybdenum (6:1)
3-Thiophenecarbonyl chloride

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα.

J. Cell. Mol. Med. 20 , 58-70, (2016)

Cullin-RING-ubiquitin-ligase (CRL)-dependent ubiquitination of the nuclear factor kappa B (NF-κB) inhibitor IκBα and its subsequent degradation by the proteasome usually precede NF-κB/RelA nuclear act...

N-(2-aminoethyl)thiophene-3-carboxamide
5-Bromo-2-ureidothiophene-3-carboxamide
2-amino-N-carbamoylthiophene-3-carboxamide
(5-PHENYL-2-UREIDO)THIOPHENE-3-CARBOXAMIDE
2-[(CHLOROACETYL)AMINO]THIOPHENE-3-CARBOXAMIDE
N-(2-Pyrazinyl)-1-benzothiophene-3-carboxamide