![]() thiophene-3-carboxamide structure
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Common Name | thiophene-3-carboxamide | ||
---|---|---|---|---|
CAS Number | 51460-47-0 | Molecular Weight | 127.16400 | |
Density | 1.302g/cm3 | Boiling Point | 313.5ºC at 760 mmHg | |
Molecular Formula | C5H5NOS | Melting Point | 181-184ºC(lit.) | |
MSDS | Chinese USA | Flash Point | 143.4ºC |
p97/VCP promotes Cullin-RING-ubiquitin-ligase/proteasome-dependent degradation of IκBα and the preceding liberation of RelA from ubiquitinated IκBα.
J. Cell. Mol. Med. 20 , 58-70, (2016) Cullin-RING-ubiquitin-ligase (CRL)-dependent ubiquitination of the nuclear factor kappa B (NF-κB) inhibitor IκBα and its subsequent degradation by the proteasome usually precede NF-κB/RelA nuclear activity. Through removal of the CRL-activating modification o... |
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