Dequalinium Chloride
Suppliers
Names
[ CAS No. ]:
522-51-0
[ Name ]:
Dequalinium Chloride
[Synonym ]:
Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride
DECA
efisol
dekamin
evazol
le chlorure de dequalinium
dekadin
EINECS 208-330-9
1,1'-Decan-1,10-diylbis(4-amino-2-methylchinolinium)dichlorid
BADQ-10
1,1'-(1,10-Decanediyl)bis(4-amino-2-methylquinolinium) dichloride
dequadin
eriosept
1,1'-Decane-1,10-diylbis(4-amino-2-methylquinolinium) dichloride
Dequalinium Chloride
dequavet
baqd10
Dequadin chloride
Quinolinium, 1,1'-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2)
MFCD00063502
Dequalinium (Chloride)
Chemical & Physical Properties
[ Melting Point ]:
≥300 °C(lit.)
[ Molecular Formula ]:
C30H40Cl2N4
[ Molecular Weight ]:
527.571
[ Exact Mass ]:
526.263000
[ PSA ]:
59.80000
[ LogP ]:
1.34060
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VA0700000
- CHEMICAL NAME :
- Quinaldinium, 1,1'-decamethylenebis(4-amino-, dichloride
- CAS REGISTRY NUMBER :
- 522-51-0
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C30-H40-N4.2Cl
- MOLECULAR WEIGHT :
- 527.64
- WISWESSER LINE NOTATION :
- T66 BKJ C1 EZ B10- BT66 BKJ C1 EZ &Q 2 &G 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18300 ug/kg
- TOXIC EFFECTS :
- Liver - fatty liver degeneration Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 82,231,1993
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1900 ug/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 8,110,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg/15W-I
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 82,231,1993
Safety Information
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
VA0700000
[ HS Code ]:
2933499090
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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Delocalized lipophilic cation dequalinium (DQA) selectively accumulates in mitochondria and displays anticancer activity in different malignancies. Our previous studies indicate a DQA-induced cytotoxi...
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Although the antinociceptive effects of N-palmitoyl-ethanolamine (PEA) were first characterized nearly 50 years ago, the identity of the mechanism that mediates these actions has not been elucidated. ...