5-Chloro-3, 4-dihydro-2H-1, 2,4-benzothiazide-7-sulfonamide-1,1-dioxide

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Names

[ CAS No. ]:
5233-42-1

[ Name ]:
5-Chloro-3, 4-dihydro-2H-1, 2,4-benzothiazide-7-sulfonamide-1,1-dioxide

[Synonym ]:
5-Chloro Hydrochlorothiazide
5,6-Dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-Dioxide
5,6-dichloro-1,1-dioxo-3,4-dihydro-2H-1
5,6-Dichloro-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide
UNII-VZ0VQ8J83H
2H-1,2,4-Benzothiadiazine-7-sulfonamide, 5,6-dichloro-3,4-dihydro-, 1,1-dioxide
5,6-Dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
5-Chloro-3, 4-dihydro-2H-1, 2,4-benzothiazide-7-sulfonamide-1,1-dioxide
Hydrochlorothiazide Impurity 1

Chemical & Physical Properties

[ Density]:
1.546g/cm3

[ Boiling Point ]:
720.3ºC at 760 mmHg

[ Molecular Formula ]:
C7H7Cl2N3O4S2

[ Molecular Weight ]:
332.18400

[ Flash Point ]:
389.4ºC

[ Exact Mass ]:
330.92600

[ PSA ]:
135.12000

[ LogP ]:
3.63080

[ Index of Refraction ]:
1.711

Safety Information

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-amino-5,6-dichlorobenzene-1,3-disulfonamide
  • Formaldehyde

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Related Compounds

  • 3-(Aminomethyl)-3-(4,6-dichloropyrimidin-5-yl)cyclobutan-1-ol
  • 2-[3-Amino-2-(chloromethyl)propoxy]-3-chloropyridine
  • 2-[3-Amino-2-(chloromethyl)propoxy]-5-bromopyridine
  • 2-{3-methyl-5-[(piperidin-3-yl)methyl]-4H-1,2,4-triazol-4-yl}propan-1-ol
  • rac-(1R,3R)-3-[2-fluoro-5-(trifluoromethyl)phenyl]-2,2-dimethylcyclopropane-1-carboxylic acid
  • 4-{[5-methyl-4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]methyl}azepane
  • 4,4-Difluoro-3-(6-fluoropyridin-3-yl)butanoic acid
  • 2-[1-(5-Methoxypyridin-3-yl)cyclopropyl]acetic acid
  • 4-Chloro-2-[2-(1-hydroxycyclopropyl)ethyl]-6-methoxyphenol
  • 1-Amino-3-(2,6-difluoro-3-methylphenyl)propan-2-ol
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