ginsenoside Rd

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Names

[ CAS No. ]:
52705-93-8

[ Name ]:
ginsenoside Rd

[Synonym ]:
GINSENOOSIDERD
ginsenoside Rd
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxyméthyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentaméthyl-17-[(2S)-6-méthyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-5-heptèn-2-yl]hexadécahydro-1H-cyclopenta[a]phénanthrén-3-yl}oxy)tétrahydro-2H-pyran-3-yl]oxy}-6-(hydroxyméthyl)tétrahydro-2H-pyran-3,4,5-triol
Herba Gynostemmatis Pentaphylli
(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl-2-O-β-D-glucopyranosyl-β-D-glucopyranoside
(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Gypenoside VIII
GinsenosideRd
EINECS 258-118-5
β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
ginsenoside--Rd standard
MFCD00210508
(2S,3R,4S,5S,6R)-2-{[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-2-({(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-5-hepten-2-yl]hexadecahydro-1H-cyclopenta[a]phenanthren-3-yl}oxy)tetrahydro-2H-pyran-3-yl]oxy}-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
1015.6±65.0 °C at 760 mmHg

[ Melting Point ]:
207 °C(dec.)

[ Molecular Formula ]:
C48H82O18

[ Molecular Weight ]:
947.154

[ Flash Point ]:
568.0±34.3 °C

[ Exact Mass ]:
946.550110

[ PSA ]:
298.14000

[ LogP ]:
3.24

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.611

[ Storage condition ]:
2-8°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ5858000
CHEMICAL NAME :
beta-D-Glucopyranoside, (3-beta,12-beta)-20-(beta-D-glucopyranosyloxy)-12-hyd roxydammar-24- en-3-yl 2-O-beta-D-glucopyranosyl-
CAS REGISTRY NUMBER :
52705-93-8
LAST UPDATED :
199312
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C48-H82-O18
MOLECULAR WEIGHT :
947.30

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
324 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,343,1975

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R22

[ Safety Phrases ]:
S2-S45

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • 6''-malonylginsenoside-Rd methyl ester
  • malonyl ginsenoside Rd
  • malonylginsenoside Rb1
  • 6''-malonylginsenoside-Rb1 methyl ester

DownStream

Articles

Transcriptome analysis of Panax vietnamensis var. fuscidicus discovers putative ocotillol-type ginsenosides biosynthesis genes and genetic markers.

BMC Genomics 16 , 159, (2015)

P. vietnamensis var. fuscidiscus, called "Yesanqi" in Chinese, is a new variety of P. vietnamensis, which was first found in Jinping County, the southern part of Yunnan Province, China. Compared with ...

Protective effects of ginsenoside Rd on PC12 cells against hydrogen peroxide.

Biol. Pharm. Bull. 31(10) , 1923-7, (2008)

Oxidative stress-induced cell damage has been implicated in a variety of neurodegenerative disorders. In the current study, we investigated the protective role of ginsenoside Rd against the cytotoxici...

Bioconversion of ginsenoside Rc into Rd by a novel α-L-arabinofuranosidase, Abf22-3 from Leuconostoc sp. 22-3: cloning, expression, and enzyme characterization.

Antonie van Leeuwenhoek 103(4) , 747-54, (2013)

A novel α-L-arabinofuranosidase (Abf22-3) that could biotransform ginsenoside Rc into Rd was obtained from the ginsenoside converting Leuconostoc sp. strain 22-3, isolated from the Korean fermented fo...


More Articles


Related Compounds

  • GINSENOSIDE RD
  • Ginsenoside Rd2
  • malonylginsenoside Rd
  • 6''-O-acetylginsenoside Rd
  • Ginsenoside Rh1
  • ginsenoside La
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