1,2,4-Trihydroxybenzene

Suppliers

Names

[ CAS No. ]:
533-73-3

[ Name ]:
1,2,4-Trihydroxybenzene

[Synonym ]:
4-Hydroxycatechol
1,2,4-Trihydroxybenzene
1,2,4-Benzenetriol
1,3,4-Benzenetriol
1,2,3-Trihydroxybenzene
benzene-1,2,3-triol
EINECS 208-575-1
Hydroxyhydroquinone
Benzene-1,2,4-triol
Benzol-1,2,3-triol
1,2,3-Benzenetriol
gallol
4-06-00-07338 (Beilstein Handbook Reference)
MFCD00002198

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
334.5±12.0 °C at 760 mmHg

[ Melting Point ]:
140 °C (subl.)(lit.)

[ Molecular Formula ]:
C6H6O3

[ Molecular Weight ]:
126.110

[ Flash Point ]:
176.9±14.2 °C

[ Exact Mass ]:
126.031693

[ PSA ]:
60.69000

[ LogP ]:
0.06

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.677

[ Water Solubility ]:
freely soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DC4200000
CHEMICAL NAME :
1,2,4-Benzenetriol
CAS REGISTRY NUMBER :
533-73-3
BEILSTEIN REFERENCE NO. :
2042863
LAST UPDATED :
199710
DATA ITEMS CITED :
17
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
QR BQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
125 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
122 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
Micronucleus test

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
10 umol/L
REFERENCE :
EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 82,81,1989

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S39-S36/37/39-S22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DC4200000

[ HS Code ]:
2907299090

Precursor & DownStream

Precursor

  • 1,2,4-Triacetoxybenzene
  • 3,4-Dichlorophenol
  • Chlorohydroquinone
  • 2,4-Dichlorophenol
  • 2L-(2,4/3,5)-2,3,4,5-tetrahydroxycyclohexan-1-one
  • Resorcine
  • 4,4-bis(ethylthio)-1,3-cyclohexanedione

DownStream

  • 4-Oxopent-2-enoic acid
  • 3H-Xanthen-3-one,2,6,7-trihydroxy-9-(2-hydroxyphenyl)-
  • 6,7-Dihydroxy-4-methyl-2H-chromen-2-one
  • 6,7-DIACETOXY-4-METHYLCOUMARIN
  • 1,3-Cyclohexanedione
  • 6,7-Dimethoxy-4-methylcoumarin
  • Hydroquinone
  • Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',3',6',7'-tetrahydroxy-
  • p-Phenylenediamine
  • 6,7-Dihydroxycoumarin-4-acetic Acid

Customs

[ HS Code ]: 2907299090

[ Summary ]:
2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Articles

A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols.

J. Dermatol. Sci. 80 , 18-24, (2015)

Tyrosinase is able to oxidize a great number of phenols and catechols to form ortho-quinones. Ortho-quinones are highly reactive compounds that exert cytotoxicity through binding with thiol enzymes an...

Degradation of sulfonamide antibiotics by Microbacterium sp. strain BR1 - elucidating the downstream pathway.

New Biotechnology 32 , 710-5, (2015)

Microbacterium sp. strain BR1 is among the first bacterial isolates which were proven to degrade sulfonamide antibiotics. The degradation is initiated by an ipso-substitution, initiating the decay of ...

The TetR-type transcriptional repressor RolR from Corynebacterium glutamicum regulates resorcinol catabolism by binding to a unique operator, rolO.

Appl. Environ. Microbiol. 78(17) , 6009-16, (2012)

The rol (designated for resorcinol) gene cluster rolRHMD is involved in resorcinol catabolism in Corynebacterium glutamicum, and RolR is the TetR-type regulator. In this study, we investigated how Rol...


More Articles

Related Compounds

  • 6-chloro-1,2,4-trihydroxybenzene
  • 5-Chloro-1,2,4-trihydroxybenzene
  • 3,5-diacetyl-1,2,4-trihydroxybenzene
  • 6-(n-pentyl)-1,2,4-trihydroxybenzene
  • 5-tert-butyl-1,2,4-trihydroxybenzene
  • 1-(2,4,5-trihydroxyphenyl)ethanone
  • N-[5-(butylsulfanyl)-1,3,4-thiadiazol-2-yl]-5-chloro-2-(ethylsulfanyl)pyrimidine-4-carboxamide
  • 5-chloro-N-{4-[ethyl(phenyl)sulfamoyl]phenyl}-2-(ethylsulfanyl)pyrimidine-4-carboxamide
  • N-(4-chlorobenzyl)-N-(furan-2-ylmethyl)furan-2-carboxamide
  • N-(4-chlorobenzyl)-N-(furan-2-ylmethyl)thiophene-2-carboxamide
  • 2-(4-bromophenoxy)-N-(4-chlorobenzyl)-N-(furan-2-ylmethyl)acetamide
  • N-(4-chlorobenzyl)-2-(4-chlorophenoxy)-N-(furan-2-ylmethyl)acetamide
  • Benzamide, N-[(4-chlorophenyl)methyl]-4-fluoro-N-(2-furanylmethyl)-
  • 2-(4-chloro-3,5-dimethylphenoxy)-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[(3-methylthiophen-2-yl)methyl]propanamide
  • 2-bromo-N-(1,1-dioxidotetrahydrothiophen-3-yl)-N-[(3-methylthiophen-2-yl)methyl]benzamide
  • N-(1,1-dioxidotetrahydrothiophen-3-yl)-2-(2-methoxyphenoxy)-N-[(3-methylthiophen-2-yl)methyl]acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.