1,2,4-Trihydroxybenzene
1,2,4-Trihydroxybenzene structure
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Common Name | 1,2,4-Trihydroxybenzene | ||
|---|---|---|---|---|
| CAS Number | 533-73-3 | Molecular Weight | 126.110 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 334.5±12.0 °C at 760 mmHg | |
| Molecular Formula | C6H6O3 | Melting Point | 140 °C (subl.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 176.9±14.2 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
Use of 1,2,4-Trihydroxybenzene1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes[1]. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | benzene-1,2,4-triol |
|---|---|
| Synonym | More Synonyms |
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes[1]. |
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| Related Catalog | |
| References |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 334.5±12.0 °C at 760 mmHg |
| Melting Point | 140 °C (subl.)(lit.) |
| Molecular Formula | C6H6O3 |
| Molecular Weight | 126.110 |
| Flash Point | 176.9±14.2 °C |
| Exact Mass | 126.031693 |
| PSA | 60.69000 |
| LogP | 0.06 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.677 |
| InChIKey | GGNQRNBDZQJCCN-UHFFFAOYSA-N |
| SMILES | Oc1ccc(O)c(O)c1 |
| Water Solubility | freely soluble |
This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.
This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.
| Symbol |
GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H315-H318-H335 |
| Precautionary Statements | P261-P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R20/21/22;R36/37/38 |
| Safety Phrases | S26-S39-S36/37/39-S22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | DC4200000 |
| HS Code | 2907299090 |
This table lists upstream starting materials and downstream derivative products related to this chemical.
| Precursor 7 | |
|---|---|
| DownStream 10 | |
CAS#:613-03-6
CAS#:95-77-2
CAS#:615-67-8
CAS#:120-83-2
CAS#:78963-40-3
CAS#:108-46-3
CAS#:112473-07-1
CAS#:4743-82-2
CAS#:3569-82-2
CAS#:529-84-0
CAS#:55939-28-1
CAS#:504-02-9
CAS#:4281-40-7
CAS#:123-31-9![Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',3',6',7'-tetrahydroxy structure](https://image.chemsrc.com/caspic/272/2320-44-7.png)
CAS#:2320-44-7
CAS#:106-50-3
CAS#:88404-14-2This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.
| HS Code | 2907299090 |
|---|---|
| Summary | 2907299090 polyphenols; phenol-alcohols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0% |
This table lists relevant public references with title, journal and publication metadata for this compound.
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A convenient screening method to differentiate phenolic skin whitening tyrosinase inhibitors from leukoderma-inducing phenols.
J. Dermatol. Sci. 80 , 18-24, (2015) Tyrosinase is able to oxidize a great number of phenols and catechols to form ortho-quinones. Ortho-quinones are highly reactive compounds that exert cytotoxicity through binding with thiol enzymes an... |
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Degradation of sulfonamide antibiotics by Microbacterium sp. strain BR1 - elucidating the downstream pathway.
New Biotechnology 32 , 710-5, (2015) Microbacterium sp. strain BR1 is among the first bacterial isolates which were proven to degrade sulfonamide antibiotics. The degradation is initiated by an ipso-substitution, initiating the decay of ... |
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The TetR-type transcriptional repressor RolR from Corynebacterium glutamicum regulates resorcinol catabolism by binding to a unique operator, rolO.
Appl. Environ. Microbiol. 78(17) , 6009-16, (2012) The rol (designated for resorcinol) gene cluster rolRHMD is involved in resorcinol catabolism in Corynebacterium glutamicum, and RolR is the TetR-type regulator. In this study, we investigated how Rol... |
This table contains target information, in‑vitro & in‑vivo assay data for this compound.
This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.
| 4-Hydroxycatechol |
| 1,2,4-Trihydroxybenzene |
| 1,2,4-Benzenetriol |
| 1,3,4-Benzenetriol |
| 1,2,3-Trihydroxybenzene |
| benzene-1,2,3-triol |
| EINECS 208-575-1 |
| Hydroxyhydroquinone |
| Benzene-1,2,4-triol |
| Benzol-1,2,3-triol |
| 1,2,3-Benzenetriol |
| gallol |
| 4-06-00-07338 (Beilstein Handbook Reference) |
| MFCD00002198 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What are the upstream materials of benzene-1,2,4-triol? |
| A: Related upstream materials(CAS) of benzene-1,2,4-triol: 613-03-6;95-77-2;615-67-8;120-83-2;78963-40-3;108-46-3;112473-07-1. |
| Q: What is the SMILES notation of benzene-1,2,4-triol? |
| A: SMILES notation of benzene-1,2,4-triol is Oc1ccc(O)c(O)c1. |
| Q: What is the English name of benzene-1,2,4-triol? |
| A: The English name of benzene-1,2,4-triol is benzene-1,2,4-triol. |
| Q: What is the boiling point of benzene-1,2,4-triol? |
| A: Boiling point of benzene-1,2,4-triol is 334.5±12.0 °C at 760 mmHg. |
| Q: What are the uses of benzene-1,2,4-triol? |
| A: Main uses of benzene-1,2,4-triol: 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes[1]. |
| Q: What is the CAS number of benzene-1,2,4-triol? |
| A: CAS number of benzene-1,2,4-triol is 533-73-3. |
| Q: What English synonyms does benzene-1,2,4-triol have? |
| A: English synonyms of benzene-1,2,4-triol: 4-Hydroxycatechol, 1,2,4-Trihydroxybenzene, 1,2,4-Benzenetriol, 1,3,4-Benzenetriol, 1,2,3-Trihydroxybenzene, benzene-1,2,3-triol, EINECS 208-575-1, Hydroxyhydroquinone, Benzene-1,2,4-triol, Benzol-1,2,3-triol, 1,2,3-Benzenetriol, gallol, 4-06-00-07338 (Beilstein Handbook Reference), MFCD00002198. |
| Q: What is the InChIKey of benzene-1,2,4-triol? |
| A: InChIKey of benzene-1,2,4-triol is GGNQRNBDZQJCCN-UHFFFAOYSA-N. |
| Q: What is the molecular weight of benzene-1,2,4-triol? |
| A: Molecular weight of benzene-1,2,4-triol is 126.110. |
| Q: What is the melting point of benzene-1,2,4-triol? |
| A: Melting point of benzene-1,2,4-triol is 140 °C (subl.)(lit.). |
This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.
| Shanghai Nianxing Industrial Co., Ltd |
| Dayang Chem (Hangzhou) Co., Ltd. |
| Henan Tianfu Chemical Co., Ltd. |