Acetohydroxamic acid

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Names

[ CAS No. ]:
546-88-3

[ Name ]:
Acetohydroxamic acid

[Synonym ]:
Acetamide, N-hydroxy-
Acetohydroxamic acid
methanecarbohydroxamic acid
EINECS 208-913-8
N-Hydroxyacetamide
N-acetylhydroxylamine
Acetomenadione
acethydroxamic acid
methylenehydroxamic acid
Acetylhydroxylamine
AHA
Lithostat
Acethydroxamsaure
MFCD00009994
Acetohydroxamic
Acetic acid,oxime
Acetic Acid Oxime

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
231.4ºC at 760 mmHg

[ Melting Point ]:
88-90 °C(lit.)

[ Molecular Formula ]:
C2H5NO2

[ Molecular Weight ]:
75.067

[ Exact Mass ]:
75.032028

[ PSA ]:
49.33000

[ LogP ]:
-1.59

[ Index of Refraction ]:
1.421

[ Stability ]:
Moisture and Temperature Sensitive

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AK8157000
CHEMICAL NAME :
Acetohydroxamic acid
CAS REGISTRY NUMBER :
546-88-3
LAST UPDATED :
199410
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C2-H5-N-O2
MOLECULAR WEIGHT :
75.08
WISWESSER LINE NOTATION :
QMV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
DOSE :
750 mg/kg
SEX/DURATION :
female 12 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Specific Developmental Abnormalities - musculoskeletal system

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
20 mmol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 152,225,1985

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H360

[ Precautionary Statements ]:
P201-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R61

[ Safety Phrases ]:
S53-S45

[ RIDADR ]:
3263

[ WGK Germany ]:
3

[ RTECS ]:
AK8157000

[ Packaging Group ]:
II

[ HS Code ]:
2942000000

Precursor & DownStream

Precursor

  • Ethanoic anhydride
  • Acetamide
  • ethyl acetate
  • 1,1-Ethanediol Diacetate
  • Sodium acetate
  • ketene
  • Acetyl chloride
  • Nitroethane
  • ACETYLURETHANE
  • hydroxylamine succinic acid salt

DownStream

  • 5-Bromobenzo[d]isoxazol-3-ylamine
  • Benzo[d]isoxazol-3-amine
  • 2-bromo-1-phenyl-1-ethanone oxime
  • 6-Bromobenzo[d]isoxazol-3-amine
  • (NZ)-N-(1-naphthalen-1-ylethylidene)hydroxylamine
  • Methyl 2-thienyl ketone oxime
  • 2,4-dimethyl-4H-quinazoline 3-oxide
  • Acetic acid,2-(aminocarbonyl)hydrazide
  • N-Methylacetamide
  • n-benzylacetamide

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • acetohydroxamic acid
  • acetohydroxamic acid
  • fluoroacetohydroxamic acid
  • O-methylacetohydroxamic acid
  • N-methylacetohydroxamic acid
  • O-methylacetohydroxamic acid
  • tert-butyl N-{4-[(3R)-3-aminobutyl]-2-chlorophenyl}carbamate
  • tert-butyl N-[1-(1-tert-butyl-1H-pyrazol-4-yl)-2-oxoethyl]-N-methylcarbamate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine