Albendazole
Suppliers
Names
[ CAS No. ]:
54965-21-8
[ Name ]:
Albendazole
[Synonym ]:
Carbamic acid, N-[5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester
Methyl hydrogen [6-(propylsulfanyl)-1H-benzimidazol-2-yl]carbonimidate
SKF62979
Methanol, 1-methoxy-1-[[6-(propylthio)-1H-benzimidazol-2-yl]imino]-, (E)-
Bilutac
MFCD00083232
ALBEN
Atasol
carbamic acid, [5-(propylthio)-1H-benzimidazol-2-yl]-, methyl ester
SK&F-62979
ZENTEL
SK&F 62979
ALBENZA
EINECS 259-414-7
methyl-5-propylthio-2-benzimidazole carbamate
Bruzol
methyl N-[5-(propylthio)-1H-benzimidazol-2-yl]carbamate
Albendazole
ZEBEN
methyl [5-(propylthio)-1H-benzimidazol-2-yl]carbamate
methyl 5-(propylthio)benzimidazol-2-ylcarbamate
5-propylthio-2-carbomethoxyaminobenzimidazole
Methyl [5-(propylsulfanyl)-1H-benzimidazol-2-yl]carbamate
methyl [5-(propylsulfanyl)-1H-1,3-benzimidazol-2-yl]carbamate
Monil
SK&F62979
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Melting Point ]:
207-211°C（分解）
[ Molecular Formula ]:
C12H15N3O2S
[ Molecular Weight ]:
265.331
[ Exact Mass ]:
265.088501
[ PSA ]:
92.31000
[ LogP ]:
3.07
[ Index of Refraction ]:
1.634
[ Storage condition ]:
0-6°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FD1100000
- CHEMICAL NAME :
- Carbamic acid, (5-(propylthio)-1H-benzimidazol-2-yl)-, methyl ester
- CAS REGISTRY NUMBER :
- 54965-21-8
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C12-H15-N3-O2-S
- MOLECULAR WEIGHT :
- 265.36
- WISWESSER LINE NOTATION :
- T56 BM DNJ CMVO1 GS3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 71 mg/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 85 mg/kg
- SEX/DURATION :
- female 8-15 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 30 mg/kg
- SEX/DURATION :
- female 10-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 60 mg/kg
- SEX/DURATION :
- female 10-12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 20 mg/kg
- SEX/DURATION :
- female 17 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)
MUTATION DATA
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Yeast - Saccharomyces cerevisiae
- DOSE/DURATION :
- 20 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 343,185,1995
Safety Information
[ Symbol ]:
GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H361-H373
[ Precautionary Statements ]:
P281
[ Target Organs ]:
Blood
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
T
[ Risk Phrases ]:
R61:May cause harm to the unborn child. R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S53-S45-S37/39-S26
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
FD1100000
[ HS Code ]:
3004909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990013
[ Summary ]:
2933990013 6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2h)-one。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
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