(−)-Scopolamine hydrochloride

Suppliers

Names

[ CAS No. ]:
55-16-3

[ Name ]:
(−)-Scopolamine hydrochloride

[Synonym ]:
scopolamine HCl
UNII-Q2P66EIP1F
Scopolamine hydrochloride
hyoscine hydrochloride
SCOPINE TROPATE
chlorhydratedescopolamine
(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0]non-7-yl (2S)-3-hydroxy-2-phenylpropanoate hydrochloride (1:1)
Benzeneacetic acid, α-(hydroxymethyl)-, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0]non-7-yl ester, (αS)-, hydrochloride (1:1)
EINECS 200-225-6
(-)-Scopolamine hydrochloride
er),hcl
SCOPINE TROPATE HYDROCHLORIDE
ScopolamineSeries
MFCD00058096

Chemical & Physical Properties

[ Boiling Point ]:
460.3ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₂₂ClNO₄

[ Molecular Weight ]:
339.814

[ Flash Point ]:
232.2ºC

[ Exact Mass ]:
339.123749

[ PSA ]:
62.30000

[ LogP ]:
1.65800

[ Storage condition ]:
?20°C

[ Water Solubility ]:
H2O: 50 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY1634501

CHEMICAL NAME :: Benzeneacetic acid, alpha-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo(3.3.1.0(sup 2,4)) non-7-yl ester, hydrochloride, (7(S)-(1-alpha,2-beta,4-beta,5-alpha,7-beta))-

CAS REGISTRY NUMBER :: 55-16-3

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C17-H21-N-O4.Cl-H

MOLECULAR WEIGHT :: 339.85

WISWESSER LINE NOTATION :: T C356 A AN DOTJ A1 HOVYR&1Q &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1275 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 88,713,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 104 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - parasympatholytic

REFERENCE :: ATXKA8 Archiv fuer Toxikologie. (Berlin, Fed. Rep. Ger.) V.15-31, 1954-74. For publisher information, see ARTODN. Volume(issue)/page/year: 29,39,1972

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300 + H310 + H330

[ Precautionary Statements ]:
P260-P264-P280-P284-P301 + P310-P302 + P350

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+: Very toxic;

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
S25-S45

[ RIDADR ]:
UN 1544

[ WGK Germany ]:
3

[ RTECS ]:
CY1634501

Articles

Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output.

J. Neurosci. 35(14) , 5680-92, (2015)

Cholinergic [acetylcholine (ACh)] axons from the basal forebrain innervate olfactory bulb glomeruli, the initial site of synaptic integration in the olfactory system. Both nicotinic acetylcholine rece...

Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives.

Acta. Pharm. 64(2) , 233-45, (2014)

Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium- 5-thiolate (10a,b) with chloroac...

Preventive effect of baicalein on methamphetamine-induced amnesia in the passive avoidance test in mice.

Pharmacology 93(5-6) , 278-85, (2014)

Methamphetamine abuse may produce cognitive impairment. Baicalein, a bioactive flavonoid, has antioxidative, anti-inflammatory and neuroprotective effects. This study examined the effects of baicalein...

N-Butyl Nor Scopolamine Hydrochloride
Scopolamine butylbromide
Methscopolamine (bromide)
Scopolamine
SCOPOLAMINE HYDROCHLORIDE, [N-METHYL-3H]
()-Apomorphine (hydrochloride hydrate)
Lithium(1+)ion4-(trifluoromethyl)pyridazine-3-carboxylate
2,2-Difluoro-2-(2-methylquinolin-4-yl)ethan-1-ol
2,2-Difluoro-1-(3-methyl-1,2-oxazol-5-yl)ethan-1-ol
5-(3-bromo-2-fluorophenyl)-1-methyl-1H-pyrazol-4-amine
2-Chloro-3,4-dimethoxybenzene-1-sulfonyl fluoride
(1S,5R,6S)-6-amino-2-oxabicyclo[3.2.0]heptan-3-one hydrochloride
(1S,5R,6S)-6-amino-2-oxabicyclo[3.2.0]heptan-3-one
3-(5-Bromo-2-methylphenyl)prop-2-en-1-ol
tert-butyl N-{1-amino-3-[5-(2-methylcyclopropyl)furan-2-yl]propan-2-yl}carbamate
2,2-Difluoro-2-(pentafluorophenyl)ethan-1-ol

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.