(−)-Scopolamine hydrochloride

(−)-Scopolamine hydrochloride Structure
(−)-Scopolamine hydrochloride structure
Common Name (−)-Scopolamine hydrochloride
CAS Number 55-16-3 Molecular Weight 339.814
Density N/A Boiling Point 460.3ºC at 760mmHg
Molecular Formula C17H22ClNO4 Melting Point N/A
MSDS Chinese USA Flash Point 232.2ºC
Symbol GHS06
GHS06
Signal Word Danger

Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output.

J. Neurosci. 35(14) , 5680-92, (2015)

Cholinergic [acetylcholine (ACh)] axons from the basal forebrain innervate olfactory bulb glomeruli, the initial site of synaptic integration in the olfactory system. Both nicotinic acetylcholine receptors (nAChRs) and muscarinic acetylcholine receptors (mACh...

Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives.

Acta. Pharm. 64(2) , 233-45, (2014)

Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and 1,3,4-thiadiazolium- 5-thiolate (10a,b) with chloroacetic acid or methyl iodide: 1,3,4-thiadiazolium-5-methylthi...

Preventive effect of baicalein on methamphetamine-induced amnesia in the passive avoidance test in mice.

Pharmacology 93(5-6) , 278-85, (2014)

Methamphetamine abuse may produce cognitive impairment. Baicalein, a bioactive flavonoid, has antioxidative, anti-inflammatory and neuroprotective effects. This study examined the effects of baicalein pretreatment on memory performance in the passive avoidanc...