2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione

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Names

[ CAS No. ]:
55003-81-1

[ Name ]:
2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione

[Synonym ]:
4-nitrothalidomide
2-(2,6-dioxo-3-piperidinyl)-5-nitro-1H-isoindole-1,3(2H)-dione
2-(2,6-dioxo-piperidin-3-yl)-5-nitro-isoindole-1,3-dione
1H-Isoindole-1,3(2H)-dione,2-(2,6-dioxo-3-piperidinyl)-5-nitro
2-(4'-Nitro-phthalimido)-glutarimid
1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline
N-(2,6-dioxopiperidin-3-yl)-4-nitrophthalimide

Chemical & Physical Properties

[ Molecular Formula ]:
C13H9N3O6

[ Molecular Weight ]:
303.23

[ Exact Mass ]:
303.04900

[ PSA ]:
132.86000

[ LogP ]:
0.73300

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Nitrophthalic anhydride
  • 3-Amino-2,6-piperidinedione hydrochloride
  • Z-Gln-OH
  • Benzyl (2,6-dioxo-3-piperidinyl)carbamate
  • 3-aminopiperidine-2,6-dione

DownStream

  • 5-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Related Compounds

  • 2-[N-ethyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methylhexanamido]-2-methylpropanoic acid
  • 2-(2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}-N-methylacetamido)butanoic acid
  • 2-(2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}-N-methylacetamido)-2-methylpropanoic acid
  • 4-(2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}acetamido)pentanoic acid
  • 2-[(2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-1,3-thiazol-4-yl}acetamido)methyl]butanoic acid
  • 4-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methylhex-4-enamido]but-2-ynoic acid
  • 2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methylhex-4-enamido]oxy}propanoic acid
  • 2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-5-methyl-N-[2-(methylsulfanyl)ethyl]hex-4-enamido]acetic acid
  • (2S)-3-(dimethylamino)-2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methyl-1H-pyrazol-5-yl]formamido}propanoic acid
  • (2S)-3-(dimethylamino)-2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-difluorobutanamido]propanoic acid
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