L-serine

Suppliers

Names

[ CAS No. ]:
56-45-1

[ Name ]:
L-serine

[Synonym ]:
L-Serin
(2R)-2-amino-3-hydroxypropanoic acid
Ser
S-serine
(S)-2-Amino-3-hydroxypropionic acid
SERINE,USP
Serine
SERINE,L
(2R)-2-Amino-3-hydroxypropionic acid
H-D-Ser-OH
L-3-Hydroxy-2-aminopropionic acid
(S)-a-Amino-b-hydroxypropionic acid
(S)-2-amino-3-hydroxypropanoic acid
Propanoic acid, 2-amino-3-hydroxy-, (S)-
H-Ser-OH
H-L-SER-OH
(S)-2-amino-3-hydroxy-Propanoic acid
2-Amino-3-hydroxypropanoic acid, (S)-
(R)-(-)-Serine
d-ser
Serine, D-
D-Serine
Serine, L-
(S)-(-)-serine
.α.-Amino-.β.-hydroxypropionic acid
L-2-Amino-3-hydroxypropionic acid
(-)-Serine
L-Serine
(R)-Serine
3-hydroxy-L-Alanine
L-Ser
EINECS 200-274-3
MFCD00064224
b-Hydroxy-L-alanine

Chemical & Physical Properties

[ Density]:
1.6

[ Boiling Point ]:
394.8±32.0 °C at 760 mmHg

[ Melting Point ]:
222ºC

[ Molecular Formula ]:
C3H7NO3

[ Molecular Weight ]:
105.093

[ Flash Point ]:
192.6±25.1 °C

[ Exact Mass ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-1.58

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.519

[ Storage condition ]:
2~8℃

[ Water Solubility ]:
250 g/L (20 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VT8100000
CHEMICAL NAME :
Serine, L-
CAS REGISTRY NUMBER :
56-45-1
BEILSTEIN REFERENCE NO. :
1721404
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C3-H7-N-O3
MOLECULAR WEIGHT :
105.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,279,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81867 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81867 No. of Facilities: 305 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 5855 (estimated) No. of Female Employees: 4144 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VT8100000

[ HS Code ]:
29225000

Synthetic Route

Precursor & DownStream

Precursor

  • l-serine methyl ester
  • (R)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
  • N-Cbz-L-Serine
  • H-Ser(Bzl)-OH
  • Z-Ser(Bzl)-OH
  • DL-Serine
  • Glycine
  • Hydroxypyruvic acid

DownStream

  • Hydroxypyruvic acid
  • L-glutamic acid
  • N-Oleoyl-L-Serine
  • Boc-Ser-OH
  • L-Cystathionine
  • Water
  • S-Phenyl-L-cysteine
  • D-methionine
  • Quisqualic acid
  • 6-Chloro-L-tryptophan

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Long-term application of glycine transporter inhibitors acts antineuropathic and modulates spinal N-methyl-D-aspartate receptor subunit NR-1 expression in rats.

Anesthesiology 121(1) , 160-9, (2014)

Dysfunction of spinal glycinergic neurotransmission is a major pathogenetic factor in neuropathic pain. The synaptic glycine concentration is controlled by the two glycine transporters (GlyT) 1 and 2....

8DSS-promoted remineralization of initial enamel caries in vitro.

J. Dent. Res. 93(5) , 520-4, (2014)

Peptides containing 8 repeats of aspartate-serine-serine (8DSS) have been shown to promote the nucleation of calcium phosphate from solution into human enamel. Here we tested the ability of 8DSS to pr...

Sulfur amino acid metabolism in Zucker diabetic fatty rats.

Biochem. Pharmacol. 96 , 256-66, (2015)

The present study was aimed to investigate the metabolomics of sulfur amino acids in Zucker diabetic fatty (ZDF) rats, an obese type 2 diabetic animal model. Plasma levels of total cysteine, homocyste...


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Related Compounds

  • L-Serine
  • L-Serine-N
  • L-Serine-C
  • L-Serine-d3
  • L-Serine-d2
  • L-Serine-d7
  • 2-Fluoro-2-(oxan-4-yl)propanedioic acid
  • 2-Fluoro-2-(oxan-4-yl)propane-1,3-diol
  • 2-Fluoro-2-(oxolan-3-yl)propane-1,3-diol
  • 4-(3-Bromo-2-fluoropropyl)oxane
  • 2-Fluoro-2-[(oxan-4-yl)methyl]propanedioic acid
  • 2-Fluoro-2-[(oxan-4-yl)methyl]propane-1,3-diol
  • 3-(3-Bromo-2-fluoropropyl)oxolane
  • 2-Fluoro-2-[(oxolan-3-yl)methyl]propanedioic acid
  • 2-Fluoro-2-[(oxolan-3-yl)methyl]propane-1,3-diol
  • 2-Fluoro-2-[(oxolan-2-yl)methyl]propanedioic acid
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