L-serine

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Names

[ CAS No. ]:
56-45-1

[ Name ]:
L-serine

[Synonym ]:
L-Serin
(2R)-2-amino-3-hydroxypropanoic acid
Ser
S-serine
(S)-2-Amino-3-hydroxypropionic acid
SERINE,USP
Serine
SERINE,L
(2R)-2-Amino-3-hydroxypropionic acid
H-D-Ser-OH
L-3-Hydroxy-2-aminopropionic acid
(S)-a-Amino-b-hydroxypropionic acid
(S)-2-amino-3-hydroxypropanoic acid
Propanoic acid, 2-amino-3-hydroxy-, (S)-
H-Ser-OH
H-L-SER-OH
(S)-2-amino-3-hydroxy-Propanoic acid
2-Amino-3-hydroxypropanoic acid, (S)-
(R)-(-)-Serine
d-ser
Serine, D-
D-Serine
Serine, L-
(S)-(-)-serine
.α.-Amino-.β.-hydroxypropionic acid
L-2-Amino-3-hydroxypropionic acid
(-)-Serine
L-Serine
(R)-Serine
3-hydroxy-L-Alanine
L-Ser
EINECS 200-274-3
MFCD00064224
b-Hydroxy-L-alanine

Chemical & Physical Properties

[ Density]:
1.6

[ Boiling Point ]:
394.8±32.0 °C at 760 mmHg

[ Melting Point ]:
222ºC

[ Molecular Formula ]:
C3H7NO3

[ Molecular Weight ]:
105.093

[ Flash Point ]:
192.6±25.1 °C

[ Exact Mass ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-1.58

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.519

[ Storage condition ]:
2~8℃

[ Water Solubility ]:
250 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VT8100000
CHEMICAL NAME :
Serine, L-
CAS REGISTRY NUMBER :
56-45-1
BEILSTEIN REFERENCE NO. :
1721404
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C3-H7-N-O3
MOLECULAR WEIGHT :
105.11

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 280,279,1992 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81867 No. of Facilities: 53 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 750 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81867 No. of Facilities: 305 (estimated) No. of Industries: 2 No. of Occupations: 9 No. of Employees: 5855 (estimated) No. of Female Employees: 4144 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VT8100000

[ HS Code ]:
29225000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • l-serine methyl ester
  • (R)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate
  • N-Cbz-L-Serine
  • H-Ser(Bzl)-OH
  • Z-Ser(Bzl)-OH
  • DL-Serine
  • Glycine
  • Hydroxypyruvic acid

DownStream

  • Hydroxypyruvic acid
  • L-glutamic acid
  • N-Oleoyl-L-Serine
  • Boc-Ser-OH
  • L-Cystathionine
  • Water
  • S-Phenyl-L-cysteine
  • D-methionine
  • Quisqualic acid
  • 6-Chloro-L-tryptophan

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Related Compounds

  • L-Serine
  • L-Serine-N
  • L-Serine-C
  • L-Serine-d3
  • L-Serine-d2
  • L-Serine-d7
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  • Ethyl 4-oxo-4-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)butanoate
  • Benzo[d][1,3]dioxol-5-yl(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone
  • (3-((3-(Thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)(2-(trifluoromethyl)phenyl)methanone
  • (Z)-3-phenyl-1-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)prop-2-en-1-one
  • 2-(4-Chlorophenoxy)-2-methyl-1-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)propan-1-one
  • 2-(2-Fluorophenoxy)-1-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)ethanone
  • 2-(Benzylthio)-1-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)ethanone
  • 2-(Naphthalen-1-yl)-1-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)ethanone
  • 3-(3-((3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl)methyl)piperidine-1-carbonyl)-2H-chromen-2-one
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