Chlorhexidine diacetate

Suppliers

Names

[ CAS No. ]:
56-95-1

[ Name ]:
Chlorhexidine diacetate

[Synonym ]:
CHLORASEPT 2000
Imidodicarbonimidic diamide, N,N''''-1,6-hexanediylbis[N'-(4-chlorophenyl)-, acetate (1:2)
UNII-5908ZUF22Y
EINECS 200-302-4
Chlorhexidine acetate
N,N''''-Hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] acetate (1:2)
N,N''''-1,6-Hexanediylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)] acetate (1:2)
MFCD00012532
chlorzoin
acetic acid,(1E)-2-[6-[[amino-[(E)-[amino-(4-chloroanilino)methylidene]amino]methylidene]amino]hexyl]-1-[amino-(4-chloroanilino)methylidene]guanidine

Chemical & Physical Properties

[ Boiling Point ]:
699.3ºC at 760mmHg

[ Melting Point ]:
153-156ºC

[ Molecular Formula ]:
C₂₆H₃₈Cl₂N₁₀O₄

[ Molecular Weight ]:
625.55

[ Flash Point ]:
376.7ºC

[ PSA ]:
204.88000

[ LogP ]:
6.37470

[ Water Solubility ]:
H2O: 15 mg/mL, clear | 1.9 g/100 mL (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DU1930000

CHEMICAL NAME :: Biguanide, 1,1'-hexamethylenebis(5-(p-chlorophenyl)-, diacetate

CAS REGISTRY NUMBER :: 56-95-1

LAST UPDATED :: 199504

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C22-H30-Cl2-N10.2C2-H4-O2

MOLECULAR WEIGHT :: 625.64

WISWESSER LINE NOTATION :: GR DMYUM&MYUM&M6MYUM&MYUM&MR DG &QV1 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(6),309,1985 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,192,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,192,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 325 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,192,1954

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 9,192,1954 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81769 No. of Facilities: 232 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1737 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81769 No. of Facilities: 76 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1050 (estimated) No. of Female Employees: 727 (estimated)

Safety Information

[ Symbol ]:

GHS07, GHS09

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H410

[ Precautionary Statements ]:
P273-P301 + P312 + P330-P391-P501

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R43

[ Safety Phrases ]:
S36/37

[ RIDADR ]:
UN 3077 9 / PGIII

[ WGK Germany ]:
3

[ RTECS ]:
DU1930000

Precursor & DownStream

Precursor

DownStream

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