Sucralose

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Names

[ CAS No. ]:
56038-13-2

[ Name ]:
Sucralose

[Synonym ]:
(2R,3R,4R,5R,6R)-2-{[(2R,3S,4S,5S)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydro-2-furanyl]oxy}-5-chloro-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4-diol
1',4,6'-Trichlorogalactosucrose
1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside
a-D-galactopyranoside, 1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-
trichlorosucrose
(2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
MFCD03648615
1,6-dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-a-D-galactopyranoside
Sucralose
EINECS 259-952-2
1,6-Dichlor-1,6-dideoxy-β-D-fructofuranosyl-4-chlor-4-deoxy-α-D-galactopyranoside
4,1',6'-Trichloro-4,1',6'-trideoxygalacto-sucrose
1,6-Dichloro-1,6-dideoxy-b-D-fructofuranosyl-4-chloro-4-deoxy-a-D-galactopyranoside
splenda
α-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-
UNII-96K6UQ3ZD4

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
669.4±55.0 °C at 760 mmHg

[ Melting Point ]:
125.5ºC

[ Molecular Formula ]:
C12H19Cl3O8

[ Molecular Weight ]:
397.634

[ Flash Point ]:
358.7±31.5 °C

[ Exact Mass ]:
396.014557

[ PSA ]:
128.84000

[ LogP ]:
0.68

[ Vapour Pressure ]:
0.0±4.6 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Storage condition ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LW5440140
CHEMICAL NAME :
alpha-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-
CAS REGISTRY NUMBER :
56038-13-2
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H19-Cl3-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>16 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TBSCDB Trends in Biochemical Sciences. (Elsevier Science Publishing Co., Inc., 655 Avenue of the Americas, New York, NY 10010) V.1- 1976- Volume(issue)/page/year: 3,61,1978

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
LW5440140

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • 4,1',6'-trichloro-4,1',6'-trideoxy-galactosucrose-6-acetate
  • 3,4-di-O-acetyl-1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactose, triacetate
  • Sucrose-6-acetic ester
  • sucrose 4-acetate
  • 1,1,1-Trimethoxyethane
  • p-Toluenesulfonic acid
  • tert-Butylamine
  • sucrose
  • D-Mannitol

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Related Compounds

  • Sucralose-d6
  • sucralose-6-acetate
  • Sucralose impurity B
  • sucralose pentaacetate
  • (3-Methyl-4-nitropyridin-2-yl)methanesulfonyl chloride
  • 1-[3-(Aminomethyl)cyclopentyl]-3-ethylurea
  • 3-(1-Methylcyclohexyl)-1,2-oxazole-5-carboxylic acid
  • 2-(2S)-2-Azetidinyl-4-fluoro-5-methylphenol
  • 3-Bromo-5-chloro-N-(2,2,2-trifluoroethyl)aniline
  • 2-(2-Chlorothiophen-3-yl)-2-methylpropanoic acid
  • benzyl N-(3-cyano-5-methylphenyl)carbamate
  • 3-(2-Hydroxy-2-methylpropyl)oxane-3-carbaldehyde
  • 1-(4-Hydroxyoxolan-3-yl)cyclopropane-1-carbaldehyde
  • 4-Ethyl-1-(prop-2-yn-1-yl)cyclohexane-1-carbaldehyde
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