Cefazedone
Suppliers
Names
[ CAS No. ]:
56187-47-4
[ Name ]:
Cefazedone
[Synonym ]:
Cefazedonum
Refosporen
Cefazedone [INN:BAN]
Cefazedonum [INN-Latin]
3-(5-Methyl-1,3,4-thiadiazolyl-2-mercaptomethyl)-7-(3,5-dichloro-4-pyridon-1-ylacetamido)-3-cephem-4-carboxylic Acid
(6R,7R)-7-{[(3,5-Dichloro-4-oxopyridin-1(4H)-yl)acetyl]amino}-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Cefazedone
(6R,7R)-7-{[(3,5-Dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino}-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
(6R)-7t-[2-(3,5-dichloro-4-oxo-4H-pyridin-1-yl)-acetylamino]-3-(5-methyl-[1,3,4]thiadiazol-2-ylsulfanylmethyl)-8-oxo-(6rH)-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[2-(3,5-dichloro-4-oxo-1(4H)-pyridinyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
MFCD01682029
Cefazedona
Refosporene
Cefazedona [INN-Spanish]
Chemical & Physical Properties
[ Density]:
1.8±0.1 g/cm3
[ Molecular Formula ]:
C18H15Cl2N5O5S3
[ Molecular Weight ]:
548.443
[ Exact Mass ]:
546.961243
[ PSA ]:
213.33000
[ LogP ]:
0.92
[ Index of Refraction ]:
1.761
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XI0372700
- CHEMICAL NAME :
- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((3,5-dichloro-4-oxo-1(4H)- pyridinyl)acetyl)amino)-3-(((5-methyl-1,3,4-thiadiazo l-2-yl)thio)methyl)-8 -oxo-, (6R-trans)-
- CAS REGISTRY NUMBER :
- 56187-47-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H15-Cl2-N5-O5-S3
- MOLECULAR WEIGHT :
- 548.46
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 88 mg/kg/17W-I
- TOXIC EFFECTS :
- Blood - normocytic anemia Blood - thrombocytopenia
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 90,135,1987