Tanshinone IIA

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Names

[ CAS No. ]:
568-72-9

[ Name ]:
Tanshinone IIA

[Synonym ]:
Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-1,6,6-trimethyl-
Tanshinone IIA
tanshinone II-A
Dan Shen Ketone
Tanshionesiia
Tanshine II
TANSHION P.E
1,6,6-Trimethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
SweetOrange
MFCD00238692
QS-D-77-4-2
TANSHINONE A
tanshiones
Tanshinone II
TANSHINONES IIA

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
480.7±44.0 °C at 760 mmHg

[ Melting Point ]:
205-207ºC

[ Molecular Formula ]:
C19H18O3

[ Molecular Weight ]:
294.344

[ Flash Point ]:
236.4±21.1 °C

[ Exact Mass ]:
294.125580

[ PSA ]:
47.28000

[ LogP ]:
5.47

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.588

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cryptotanshinone
  • 5-Bromo-2-methyl-2-pentene
  • bromoanisole
  • 1,1-dimethyl-5-tetralol
  • 5-methoxy-1,1-dimethyl-tetralin
  • Anisole
  • 1-(1'-methoxyphenyl)-4-methylpent-3-ene
  • 1-(5,5-dimethyl-5,6,7,8-tetrahydro-1-naphthyl)ethan-1-one

DownStream

Articles

The CO donor CORM-2 inhibits LPS-induced vascular cell adhesion molecule-1 expression and leukocyte adhesion in human rheumatoid synovial fibroblasts.

Br. J. Pharmacol. 171(12) , 2993-3009, (2014)

Infection with Gram-negative bacteria has been recognized as an initiator of rheumatoid arthritis, which is characterized by chronic inflammation and infiltration of immune cells. Carbon monoxide (CO)...

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

J. Nat. Prod. 76(1) , 36-44, (2013)

The roots of Salvia miltiorrhiza ("Danshen") are used in traditional Chinese medicine for the treatment of numerous ailments including cardiovascular disease, hypertension, and ischemic stroke. Extrac...

Surfactant-coated graphitized multiwalled carbon nanotubes as the pseudostationary phase in electrokinetic chromatography for the analysis of phytochemical compounds in biological fluids.

Electrophoresis 36(7-8) , 1055-63, (2015)

This report describes the use of surfactant-coated graphitized multiwalled carbon nanotubes (SC-GMWNTs) as a novel pseudostationary phase in CE with diode array detection for the determination of phen...


More Articles

Related Compounds

  • tanshinone IIA
  • Isotanshinone IIA
  • Hydroxytanshinone IIA
  • Tanshinone IIA anhydride
  • Tanshinone IIA sodium sulfonate
  • tanshinone VI
  • 4-Amino-1-(2-phenylcyclopropyl)pyrrolidin-2-one
  • 2-Bromo-1-(3-chloropropyl)-4-fluorobenzene
  • Methyl 5-(aminosulfonyl)-2-chloro-4-[(2-furanylmethyl)amino]benzoate
  • 3-(2-Bromo-5-fluorophenyl)propan-1-OL
  • 3-(3-Chloro-2,6-difluorophenyl)propanal
  • (2-(Difluoromethoxy)phenyl)propanal
  • 3-[2-Fluoro-5-(trifluoromethyl)phenyl]propan-1-OL
  • N-[5-amino-6-(1H-benzimidazol-2-yl)pyrazin-2-yl]acetamide
  • 3-(5'-Bromo-2'-(difluoromethoxy)phenyl)propionaldehyde
  • 3-[5-Fluoro-2-(trifluoromethyl)phenyl]propan-1-amine
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