tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

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Names

[ CAS No. ]:
571188-59-5

[ Name ]:
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate

[Synonym ]:
tert-Butyl-4-(6-aminopyridin-3-yl)piperazin-1-carboxylat
tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
TERT BUTYL-4-(6-AMINOPYRIDIN-3-YL)PIPERAZINE-1-CARBOXYLATE
4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
Ribociclib Intermediate 4

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
454.1±45.0 °C at 760 mmHg

[ Melting Point ]:
130-132℃

[ Molecular Formula ]:
C14H22N4O2

[ Molecular Weight ]:
278.350

[ Flash Point ]:
228.4±28.7 °C

[ Exact Mass ]:
278.174286

[ PSA ]:
71.69000

[ LogP ]:
1.23

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.569

[ Storage condition ]:
2~8℃

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-(6-Nitro-3-pyridinyl)-1-piperazinecarboxylic acid tert-butyl ester
  • 5-Bromo-2-nitropyridine
  • 1-(6-Nitropyridin-3-yl)piperazin
  • N-Boc-piperazine
  • Di-tert-butyl dicarbonate
  • 2-Amino-5-fluoropyridine
  • 5-Fluoro-2-nitropyridine

DownStream

  • 2-Methyl-2-propanyl 4-(6-{[5-bromo-4-(cyclopentylamino)-2-pyrimid inyl]amino}-3-pyridinyl)-1-piperazinecarboxylate
  • 4-[6-[(6-Bromo-8-cyclopentyl-7,8-dihydro-5-methyl-7- oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-1- piperazinecarboxylic acid 1,1-dimethylethyl ester
  • ETHYL 2-((5-(4-(TERT-BUTOXYCARBONYL)PIPERAZIN-1-YL)PYRIDIN-2-YL)AMINO)-8-CYCLOPENTYL-5-METHYL-7-OXO-7,8-DIHYDROPYRIDO[2,3-D]PYRIMIDINE-6-CARBOXYLATE

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-(5-Amino-2-methoxyphenyl)-2-[2,4-DI(tert-butyl)-phenoxy]acetamide
  • N-(3-Amino-2-methylphenyl)-2-(isopentyloxy)-benzamide
  • N-(3-Amino-2-methylphenyl)-4-(2,4-dichlorophenoxy)butanamide
  • N-(3-Amino-2-methylphenyl)-2-(2-isopropyl-5-methylphenoxy)acetamide
  • 4-Isocyanato-4,5,6,7-tetrahydro-1-benzothiophene
  • tert-Butyl N-(4-mesityl-3-pyridyl)carbamate
  • 6-(Aminomethyl)-4-(3,5-dichlorophenyl)-3-morpholinone
  • 6-Cyclohexyl-1,2,3,4-tetrahydroisoquinoline
  • Pantoprazole(1-)
  • 4-Methyl-4-phenylpentane-2-sulfonyl chloride
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