2-Bromo-3-nitrobenzoic acid

Names

[ CAS No. ]:
573-54-6

[ Name ]:
2-Bromo-3-nitrobenzoic acid

[Synonym ]:
EINECS 209-356-3
MFCD00074899
2-Bromo-3-nitrobenzoic acid
Benzoic acid, 2-bromo-3-nitro-

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
337.7±32.0 °C at 760 mmHg

[ Melting Point ]:
184-186 °C(lit.)

[ Molecular Formula ]:
C₇H₄BrNO₄

[ Molecular Weight ]:
246.02

[ Flash Point ]:
158.1±25.1 °C

[ Exact Mass ]:
244.932358

[ PSA ]:
83.12000

[ LogP ]:
1.88

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.650

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2-Amino-3-nitrobenzoic acid
2-PHENYLAMINO-3-NITROBENZOIC ACID
2-Bromo-3-nitrobenzaldehyde
Phenoxazine-1-carboxylic acid,6-(trifluoromethyl)- (8CI)
2-bromo-1-nitro-3-(trifluoromethyl)benzene
2-Hydroxy-3-nitrobenzoic acid
Methyl 2-bromobenzoate
6-(2,3-dimethylbut-2-en-1-yl)-5-methyl-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2-ol
6-(2-Isopropoxyethyl)-5-methyl-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one
6-(2-benzylprop-2-en-1-yl)-5-methyl-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepin-2-ol

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

One-pot tandem Hurtley-retro-Claisen-cyclisation reactions in the synthesis of 3-substituted analogues of 5-aminoisoquinolin-1-one (5-AIQ), a water-soluble inhibitor of PARPs.

Bioorg. Med. Chem. 21(17) , 5218-27, (2013)

Poly(ADP-ribose)polymerase-1 (PARP-1) is an important target for drug design for several therapeutic applications. 5-Aminoisoquinolin-1-one (5-AIQ) is a highly water-soluble lead compound; synthetic r...

Preparation and NMR analysis of 2, 6-heterodifunctional halobenzenes as precursors for substituted biphenyls Sienkowska M, et al.

Tetrahedron 56(2) , 165-73, (2000)