7-Hydroxy-4-(trifluoromethyl)coumarin

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Names

[ CAS No. ]:
575-03-1

[ Name ]:
7-Hydroxy-4-(trifluoromethyl)coumarin

[Synonym ]:
7-Hydroxy-4-(trifluoromethyl)-2H-1-benzopyran-2-one
7-Hydroxy-4-(trifluoromethyl)-2H-chromen-2-one
7-hydroxy-4-(trifluoromethyl)chromen-2-one
2H-1-Benzopyran-2-one, 7-hydroxy-4-(trifluoromethyl)-
MFCD00037578

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
311.4±42.0 °C at 760 mmHg

[ Melting Point ]:
178-180 °C(lit.)

[ Molecular Formula ]:
C₁₀H₅F₃O₃

[ Molecular Weight ]:
230.140

[ Flash Point ]:
142.2±27.9 °C

[ Exact Mass ]:
230.019073

[ PSA ]:
50.44000

[ LogP ]:
2.88

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.546

[ Water Solubility ]:
DMF: soluble

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300-H315-H319-H335

[ Precautionary Statements ]:
P261-P264-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25;R36/37/38

[ Safety Phrases ]:
S26-S36-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethyl trifluoroacetoacetate
Resorcine
Ethyl 5,5,5-trifluoro-4-oxopentanoate
7-Benzyloxy-4-(trifluoromethyl)coumarin
7-Methoxy-4-(trifluoromethyl)coumarin
2,4-dibromo-6-((4,5-dimethoxy-2-nitrobenzyl)oxy)-3-methyl-5-(((((2-oxo-4-(trifluoromethyl)-2H-chromen-7-yl)oxy)carbonyl)oxy)methyl)benzyl (6,8-dichloro-9,9-dimethyl-7-oxo-7,9-dihydroacridin-2-yl) carbonate

DownStream

7-Benzyloxy-4-(trifluoromethyl)coumarin
4-Trifluoromethylumbelliferyl Tetra-O-acetylated α-D-N-Acetylneuraminate Methyl Ester
7-Methoxy-4-(trifluoromethyl)coumarin

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

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