4-Bromo-2-fluorobenzaldehyde

Suppliers

Names

[ Name ]:
4-Bromo-2-fluorobenzaldehyde

[Synonym ]:
4-bromo-6-fluorobenzaldehyde
Benzaldehyde, 4-bromo-2-fluoro-
VHR BF DE
MFCD00143261
4-Brom-2-fluorbenzolcarbaldehyd
4-Bromo-2-fluorobenzaldehyde
2-Fluoro-4-bromobenzaldehyde
4-bromo2-fluorobenzaldehyde
benzaldehyde,4-bromo-2-fluoro

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
241.4±25.0 °C at 760 mmHg

[ Melting Point ]:
59-64 °C

[ Molecular Formula ]:
C₇H₄BrFO

[ Molecular Weight ]:
203.008

[ Flash Point ]:
99.8±23.2 °C

[ Exact Mass ]:
201.942947

[ PSA ]:
17.07000

[ LogP ]:
2.71

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.585

[ Storage condition ]:
Room temperature.

[ Water Solubility ]:
INSOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S37/39-S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2913000090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(4-Bromo-2-fluorophenyl)methanol
2,5-Dibromofluorobenzene
N,N-Dimethylformamide
N-(4-bromo-2-fluoro-benzyl)-acetamide
4-bromo-2-fluorobenzaldoxime
1-Bromo-3-fluorobenzene
4-Bromo-3-fluorobenzoic acid
4-Bromo-3-fluorotoluene

DownStream

6-bromo-1,3-dimethylindazole
ethyl 6-bromobenzo[b]thiophene-2-carboxylate
4-Bromo-2-methoxybenzaldehyde
4-bromo-2-fluorobenzaldoxime
Methyl 6-bromo-1-benzothiophene-2-carboxylate
1-(4-Bromo-2-fluorophenyl)-1-propanone
2-(4-Bromo-2-fluorophenyl)-1,3-dioxolane
4-BROMO-2-FLUOROPHENYL CYCLOPROPYL KETONE
6-Bromoindazole
4-BROMO-2-PIPERIDINOBENZENECARBALDEHYDE

Customs

[ HS Code ]: 2913000090

[ Summary ]:
HS: 2913000090 halogenated, sulphonated, nitrated or nitrosated derivatives of products of heading 2912 Educational tariff:17.0% Tax rebate rate:9.0% Regulatory conditions:none Most favored nation tariff:5.5% General tariff:30.0%

Articles

Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors.

Arch. Pharm. (Weinheim) 344(6) , 372-85, (2011)

Aldose reductase (ARL2) is the first enzyme in the polyol pathway which catalyzes the NADPH-dependent reduction of glucose to sorbitol. Its involvement on diabetic complications makes this enzyme a ch...

Synthesis of tri-substituted biaryl based trianglimines: formation of C3-symmetrical and non-symmetrical regioisomers.

Org. Biomol. Chem. 9(9) , 3258-71, (2011)

2-Functionalised aromatic monoaldehydes were synthesised in good to excellent yields by reacting 4-bromo-2-fluorobenzaldehyde with different secondary amines and phenol. The Suzuki-coupling reaction o...

Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.

Bioorg. Med. Chem. Lett. 17(17) , 4799-803, (2007)

The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described.