4-Bromo-2-fluorobenzaldehyde
4-Bromo-2-fluorobenzaldehyde structure
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Common Name | 4-Bromo-2-fluorobenzaldehyde | ||
|---|---|---|---|---|
| CAS Number | 57848-46-1 | Molecular Weight | 203.008 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 241.4±25.0 °C at 760 mmHg | |
| Molecular Formula | C7H4BrFO | Melting Point | 59-64 °C | |
| MSDS | USA | Flash Point | 99.8±23.2 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Synthesis and biological evaluation of 2'-oxo-2,3-dihydro-3'H- spiro[chromene-4,5'-[1,3]oxazolidin]-3'yl]acetic acid derivatives as aldose reductase inhibitors.
Arch. Pharm. (Weinheim) 344(6) , 372-85, (2011) Aldose reductase (ARL2) is the first enzyme in the polyol pathway which catalyzes the NADPH-dependent reduction of glucose to sorbitol. Its involvement on diabetic complications makes this enzyme a challenge therapeutic target widely investigated to limit and... |
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Synthesis of tri-substituted biaryl based trianglimines: formation of C3-symmetrical and non-symmetrical regioisomers.
Org. Biomol. Chem. 9(9) , 3258-71, (2011) 2-Functionalised aromatic monoaldehydes were synthesised in good to excellent yields by reacting 4-bromo-2-fluorobenzaldehyde with different secondary amines and phenol. The Suzuki-coupling reaction of the newly functionalised aromatic monoaldehydes with 4-fo... |
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Benzylamine histamine H(3) antagonists and serotonin reuptake inhibitors.
Bioorg. Med. Chem. Lett. 17(17) , 4799-803, (2007) The design, synthesis, and in vitro activity of a series of novel 5-ethynyl-2-aryloxybenzylamine-based histamine H(3) ligands that are also serotonin reuptake transporters is described. |
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The synthesis and biological evaluation of a novel series of antimicrobials of the oxazolidinone class.
Bioorg. Med. Chem. Lett. 12(16) , 2121-3, (2002) A novel series of antimicrobials of the oxazolidinone class is disclosed. These compounds are characterized relative to previously described analogues by a 'halostilbene-derived' pharmacophore and demonstrate enhanced antimicrobial activity against key Gram-p... |