Inosine
Suppliers
Names
[ CAS No. ]:
58-63-9
[ Name ]:
Inosine
[Synonym ]:
6-Oxopurine riboside
HXR
RIBOXINE
nosine
Ino
EINECS 200-390-4
9-β-δ-Ribofuranosylhypoxanthine
Hypoxanthine, 9-β-D-ribofuranosyl-
1,9-dihydro-9-b-D-ribofuranosyl-6H-Purin-6-one
9-β-D-ribofuranosyl-Hypoxanthine
9-β-D-Ribofuranosylhypoxanthine
Inosie
9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxyméthyl)tétrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one
INO 495
hypoxanthine
Oxiamin
9-b-D-Ribofuranosylhypoxanthine
Atorel
MFCD00066770
6H-Purin-6-one, 1,9-dihydro-9-β-D-ribofuranosyl-
9β-D-Ribofuranosylhypoxanthine
6-oxy-purine riboside
9H-Purin-6-ol, 9-β-D-ribofuranosyl-
9-β-D-ribofuranosyl-1,9-dihydro-6H-purin-6-one
9-b-D-ribofuranosyl-Hypoxanthine
Inosine
9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-1,9-dihydro-6H-purin-6-one
T56 BN DN FN HNJ IQ D- BT5OTJ CQ DQ E1Q &&β-D-Ribo Form
Inosine (8CI,9CI)
Selfer
Chemical & Physical Properties
[ Density]:
2.1±0.1 g/cm3
[ Boiling Point ]:
670.5±65.0 °C at 760 mmHg
[ Melting Point ]:
222-226 °C (dec.)(lit.)
[ Molecular Formula ]:
C10H12N4O5
[ Molecular Weight ]:
268.226
[ Flash Point ]:
359.3±34.3 °C
[ Exact Mass ]:
268.080780
[ PSA ]:
133.49000
[ LogP ]:
-1.91
[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C
[ Index of Refraction ]:
1.879
[ Water Solubility ]:
2.1 g/100 mL (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NM7460000
- CHEMICAL NAME :
- Inosine
- CAS REGISTRY NUMBER :
- 58-63-9
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C10-H12-N4-O5
- MOLECULAR WEIGHT :
- 268.26
- WISWESSER LINE NOTATION :
- T56 BN DN FN HNJ IQ D- BT5OTJ CQ DQ E1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >20 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3175 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 558 gm/kg/93D-C
- TOXIC EFFECTS :
- Endocrine - changes in thymus weight Blood - normocytic anemia Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 60 mmol/L
- REFERENCE :
- PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 48,686,1962 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4726 No. of Facilities: 121 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1253 (estimated) No. of Female Employees: 904 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
NM7460000
[ HS Code ]:
2934999090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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