2-Naphthylacetic acid

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Names

[ CAS No. ]:
581-96-4

[ Name ]:
2-Naphthylacetic acid

[Synonym ]:
2-Naphthaleneacetic acid
2-Naphthylacetic acid
naphthalen-2-ylacetic acid
2-Naphthalene acetic acid
2-naphthalen-2-ylacetic acid
EINECS 209-475-0
MFCD00004126

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
373.2±11.0 °C at 760 mmHg

[ Melting Point ]:
141-143 °C(lit.)

[ Molecular Formula ]:
C12H10O2

[ Molecular Weight ]:
186.207

[ Flash Point ]:
270.1±14.4 °C

[ Exact Mass ]:
186.068085

[ PSA ]:
37.30000

[ LogP ]:
2.74

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.652

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QJ0876000
CHEMICAL NAME :
2-Naphthaleneacetic acid
CAS REGISTRY NUMBER :
581-96-4
LAST UPDATED :
198502
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C12-H10-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 116,154,1958

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QJ0876000

[ HS Code ]:
29163900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • carbon monoxide
  • 2-(Chloromethyl)naphthalene
  • 2-Naphthaleneaceticacid, ethyl ester
  • 2-Naphthalenemethanol
  • 2,2,2-trichloro-1-napthalen-2-yl-ethanol
  • 2-(brommethyl)naphthalen
  • Carbon dioxide
  • naphthalen-2-ylmethyl acetate
  • 1-Naphthylacetonitrile

DownStream

  • 2-Naphthylacetyl chloride
  • (S)-VAPOL
  • 2-naphthalen-2-ylcyclopenta[b]naphthalene-1,3-dione
  • Naphthalene,2-(2-bromoethyl)-
  • N-methyl-2-naphthalen-2-ylacetamide
  • 1,2-Bis(2-naphtyl)ethane
  • 2-Methylnaphthalene
  • 2-Vinylnaphthalene
  • 2-Naphthaldehyde
  • propyl 2-naphthalen-2-ylacetate

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • 2-AMINO-2-NAPHTHYLACETIC ACID
  • α-methoxy-2-naphthylacetic acid
  • 2-naphthylacetic acid methyl ester
  • 2-(S)-methyl-2-naphthylacetic acid
  • (R)-|A-Methoxy-2-naphthylacetic acid
  • sodium salt of 2-naphthylacetic acid
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  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
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  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
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  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine