2-Naphthylacetic acid

2-Naphthylacetic acid Structure
2-Naphthylacetic acid structure
Common Name 2-Naphthylacetic acid
CAS Number 581-96-4 Molecular Weight 186.207
Density 1.2±0.1 g/cm3 Boiling Point 373.2±11.0 °C at 760 mmHg
Molecular Formula C12H10O2 Melting Point 141-143 °C(lit.)
MSDS Chinese USA Flash Point 270.1±14.4 °C
Symbol GHS07
GHS07
Signal Word Warning

D-amino acids modulate the cellular response of enzymatic-instructed supramolecular nanofibers of small peptides.

Biomacromolecules 15(10) , 3559-68, (2014)

Peptides made of D-amino acids, as the enantiomer of corresponding L-peptides, are able to resist proteolysis. It is, however, unclear or much less explored whether or how D-amino acids affect the cellular response of supramolecular nanofibers formed by enzym...

Differentiation of esterases reacting with organophosphorus compounds.

Chem. Biol. Interact. 87(1-3) , 77-83, (1993)

The hydrolysis of paraoxon (POX), phenylacetate (PA) and beta-naphthylacetate (BNA) was studied in human serum. Based upon correlations between enzyme activities, upon reversible inhibition by EDTA and upon progressive inhibition by iso-OMPA, tabun, eserine a...

Ceramide participates in lysosome-mediated cell death induced by type II anti-CD20 monoclonal antibodies.

Leuk. Lymphoma 56 , 1863-8, (2015)

Considering the variable and often modest therapeutic efficacy of rituximab for a substantial proportion of patients suffering from non-Hodgkin lymphomas (NHLs), various type II anti-CD20 monoclonal antibodies (mAbs) with excellent ability in inducing program...

The hydrolytic activity of esterases in the yeast Saccharomyces cerevisiae is strain dependent.

Cell Biol. Int. 35(11) , 1111-9, (2011)

Ester precursors of fluorogenic or chromogenic probes are often employed in studies of yeast cell biology. This study was aimed at a comparison of the ability of several commonly used laboratory wild-type Saccharomyces cerevisiae strains to hydrolyse the foll...

Substrate specificity and enantioselectivity of arylcarboxylic acid glucuronidation.

Drug Metab. Dispos. 16(4) , 627-34, (1988)

A general and sensitive HPLC method using a precolumn switching system was developed for the separation and quantification of the individual diastereoisomeric glucuronides of the 2-phenylpropionic acid optical isomers. Kinetic properties of rat liver glucuron...

Effect of urea on the enzymatic activity of a lipase entrapped in AOT-heptane-water reverse micellar solutions.

J. Colloid. Interface Sci. 283(1) , 87-93, (2005)

A study has been made of the effect of urea upon the hydrolysis of 2-naphthyl acetate (2-NA) catalyzed by lipase from Rhizopus arrhizus in AOT-heptane-water reverse micellar solutions at pH 7. The partition constants, K, of 2-NA between n-heptane and aqueous ...

Studies on the metabolism of arylacetic acids. 6. Comparative metabolic conjugation of 1- and 2-naphthylacetic acids in the guinea pig, mouse, hamster and gerbil.

Xenobiotica 17(7) , 815-21, (1987)

The patterns of metabolic conjugation of the isomeric 1- and 2-naphthylacetic acids have been compared in guinea pig, mouse, hamster and gerbil. Equimolar doses of [carboxy-14C]1- and 2-naphthylacetic acids were given to these species by i.p. injection, their...

Studies on the metabolism of arylacetic acids. 7. The influence of varying dose size upon the conjugation pattern of 2-naphthylacetic acid in the guinea pig, mouse and hamster.

Xenobiotica 17(7) , 823-8, (1987)

1. The influence of dose size upon the metabolic conjugation of 2-naphthylacetic acid with various amino acids and glucuronic acid has been studied in the guinea pig, mouse and hamster. 2. Guinea pigs conjugated 2-naphthylacetic acid with glycine and glucuron...

A plug and play polymeric template driven by supramolecular interactions.

J. Biomed. Mater. Res. A 100(1) , 149-54, (2012)

A new "plug and play" polymeric template with the driving force of host-guest interaction between β-CD and naphthalene-modified functional groups was designed and studied. Multiple functional groups can be loaded into the template directly and conveniently. I...

Auxin binding proteins from maize coleoptiles: purification and molecular characterization.

Symp. Soc. Exp. Biol. 44 , 299-313, (1990)

To understand precisely the mechanisms by which hormones like auxins regulate plant differentiation and development, it is essential to isolate putative hormone receptors. We have purified the major auxin binding protein from maize coleoptiles to homogeneity....