Ofurace

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Names

[ CAS No. ]:
58810-48-3

[ Name ]:
Ofurace

[Synonym ]:
Acetamide, 2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)-
EINECS 261-451-9
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furyl)acetamide
2-chloro-2',6'-dimethyl-N-(2-oxo-tetrahydro-3-furanyl)-acetanilide
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2-oxo-3-furanyl)acetamide
2-chloro-N-(2,6-dimethylphenyl)-N-(2-oxooxolan-3-yl)acetamide
MFCD01632753
1653655
2-Chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide
N-(tetrahydrofuran-2-on-3-yl)-N-(2,6-dimethylphenyl)-2-chloroacetamide
2-Chlor-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamid
rac-2-chloro-N-(2,6-dimethylphenyl)-N-[(3R)-2-oxooxolan-3-yl]acetamide
2-chloro-N-(2,6-dimethyl-phenyl)-N-(2-oxo-tetrahydro-furan-3-yl)-acetamide
Ofurace [ANSI:BSI:ISO]
(RS)-α-(2-Chloro-N-2,6-xylylacetamido)-γ-butyrolactone
2-Chloro-N-(2,6-dimethylphenyl)-N-(2-oxotetrahydro-3-furanyl)acetamide
Ofurace
Milfuram
2-chloro-N-(2,6-dimethylphenyl)-N-(tetrahydro-2--oxo-3-furanyl)-acetamide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
482.7±45.0 °C at 760 mmHg

[ Melting Point ]:
145 - 146ºC

[ Molecular Formula ]:
C14H16ClNO3

[ Molecular Weight ]:
281.73

[ Flash Point ]:
245.8±28.7 °C

[ Exact Mass ]:
281.081879

[ PSA ]:
46.61000

[ LogP ]:
0.93

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.589

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AE1300200
CHEMICAL NAME :
Acetanilide, 2-chloro-2',6'-dimethyl-N-(2-oxotetrahydro-3-furyl)-
CAS REGISTRY NUMBER :
58810-48-3
BEILSTEIN REFERENCE NO. :
1653655
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C14-H16-Cl-N-O3
MOLECULAR WEIGHT :
281.76

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C223,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 35,343,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - domestic
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 35,343,1981

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
AE1300200

Articles

Effect of ofurace, oxadixyl, and alachlor on xenobiotic biotransformation in the rat liver.

Arch. Environ. Contam. Toxicol. 18(6) , 876-80, (1989)

Ofurace, oxadixyl, and alachlor were studied for their effect on hepatic xenobiotic biotransformation in male rats by dosing i.p. with 1 or 100 mg/kg of chemical for 7 days. Ofurace decreased ethoxyre...


More Articles


Related Compounds

  • 2-(3,5-Difluoro-4-methoxyphenyl)-2-oxoacetic acid
  • 2-(3,4-Difluoro-2-methoxyphenyl)-2-oxoacetic acid
  • 2-(3,5-Difluoro-2-methoxyphenyl)-2-oxoacetic acid
  • 1-(2,4,5-Trifluorophenyl)cyclopropane-1-carboxylic acid
  • 2-Amino-1-{4-[(difluoromethyl)sulfanyl]phenyl}ethan-1-ol
  • Methyl 2-(2,5-difluoro-4-methylphenyl)-2-hydroxyacetate
  • 1-(2,4-Difluoro-3,5-dimethoxyphenyl)ethan-1-one
  • 2-Amino-1-{3-[(difluoromethyl)sulfanyl]phenyl}ethan-1-ol
  • 2,3-Difluoro-4-(2-hydroxypropan-2-yl)benzoic acid
  • 2-(3,6-Difluoro-2-methoxyphenyl)propanoic acid
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