N-ACETYLTHIOUREA
Suppliers
Names
[ CAS No. ]:
591-08-2
[ Name ]:
N-ACETYLTHIOUREA
[Synonym ]:
N-acetyl thiourea
Acetothiourea
MFCD00004937
1-Acetylthiourea
Ethanesulfenamide, N-(aminocarbonyl)-1-oxo-
Urea,1-acetyl-2-thio
Acetylthiourea
1-(Acetylsulfanyl)urea
N'-acetyltbiocarbamide
N-Acetylthiocarbamide
EINECS 209-699-9
1-ACETYL-2-THIOUREA
N-acetyl-2-thiourea
N-ACETYLTHIOUREA
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
208.6ºC at 760 mmHg
[ Melting Point ]:
165-169 °C(lit.)
[ Molecular Formula ]:
C3H6N2O2S
[ Molecular Weight ]:
134.157
[ Exact Mass ]:
134.014999
[ PSA ]:
87.21000
[ LogP ]:
-0.60
[ Index of Refraction ]:
1.543
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YR7700000
- CHEMICAL NAME :
- Urea, 1-acetyl-2-thio-
- CAS REGISTRY NUMBER :
- 591-08-2
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C3-H6-N2-O-S
- MOLECULAR WEIGHT :
- 118.17
- WISWESSER LINE NOTATION :
- SUYZMV1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,478,1949
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300
[ Precautionary Statements ]:
P264-P301 + P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
S36/37/39-S45
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
YR7700000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Lab. Delo (9) , 15-8, (1989)
The authors have examined the possibility of replacing sodium arsenite with acetyl thiourea and of using butanol acidified with phosphoric acid in measuring sialic acids in biologic material. The resu...
J. Phys. Chem. A 110(7) , 2396-410, (2006)
The oxidation reactions of N-acetylthiourea (ACTU) by chlorite and chlorine dioxide were studied in slightly acidic media. The ACTU-ClO(2)(-) reaction has a complex dependence on acid with acid cataly...
Carbohydr. Res. 344(1) , 134-5, (2009)
Treatment with concd HCl/MeOH transformed N-(tetra-O-acetyl-beta-D-glucopyranosyl)-N'-acetylthiourea, via selective cleavage of the primary alcoholic ester group, into the title compound.