N-ACETYLTHIOUREA structure
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Common Name | N-ACETYLTHIOUREA | ||
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CAS Number | 591-08-2 | Molecular Weight | 134.157 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 208.6ºC at 760 mmHg | |
Molecular Formula | C3H6N2O2S | Melting Point | 165-169 °C(lit.) | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS06 |
Signal Word | Danger |
Name | N-carbamothioylacetamide |
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Synonym | More Synonyms |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 208.6ºC at 760 mmHg |
Melting Point | 165-169 °C(lit.) |
Molecular Formula | C3H6N2O2S |
Molecular Weight | 134.157 |
Exact Mass | 134.014999 |
PSA | 87.21000 |
LogP | -0.60 |
Index of Refraction | 1.543 |
Synonym:Acetamide, N-(aminothioxomethyl)-; Acetothiourea; Acetylthiocarbamide; N-Acetylthiocarbamide; Acetyl thiourea; 1-Acetylthiourea; 1-Acetyl-2-thiourea; Urea, 1-acetyl-2-thio Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 23/24/25 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Toxic by inhalation, in contact with skin and if swallowed.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May cause allergic contact dermatitis. Ingestion: May be fatal if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause irritation of the mucous membranes. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Induce vomiting only when instructed to do so by a physician. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. Do not use mouth-to-mouth resuscitation if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Wash area with soap and water. Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use only in a chemical fume hood. Discard contaminated shoes. Storage: Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightly closed. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 591-08-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystals Color: white Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 165.00 - 169.00 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Soluble in hot water. Specific Gravity/Density: Not available. Molecular Formula: CH3CONHCSNH2 Molecular Weight: 118.15 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 591-08-2: YR7700000 LD50/LC50: CAS# 591-08-2: Oral, rat: LD50 = 50 mg/kg. Carcinogenicity: N-Acetylthiourea - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Other No information available. Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: II IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: II RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: II USA RQ: CAS# 591-08-2: 1000 lb final RQ; 454 kg final RQ Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: T Risk Phrases: R 23/24/25 Toxic by inhalation, in contact with skin and if swallowed. Safety Phrases: S 23 Do not inhale gas/fumes/vapour/spray. S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 591-08-2: No information available. Canada CAS# 591-08-2 is listed on Canada's NDSL List. CAS# 591-08-2 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 591-08-2 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H300 |
Precautionary Statements | P264-P301 + P310 |
Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
Hazard Codes | T:Toxic; |
Risk Phrases | R23/24/25 |
Safety Phrases | S36/37/39-S45 |
RIDADR | UN 2811 6.1/PG 2 |
WGK Germany | 3 |
RTECS | YR7700000 |
Packaging Group | II |
Hazard Class | 6.1 |
Precursor 9 | |
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DownStream 10 | |
[Modification of the thiobarbituric method for determining sialic acids in biological material].
Lab. Delo (9) , 15-8, (1989) The authors have examined the possibility of replacing sodium arsenite with acetyl thiourea and of using butanol acidified with phosphoric acid in measuring sialic acids in biologic material. The resu... |
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Oxyhalogen-sulfur chemistry: kinetics and mechanism of oxidation of N-acetylthiourea by chlorite and chlorine dioxide.
J. Phys. Chem. A 110(7) , 2396-410, (2006) The oxidation reactions of N-acetylthiourea (ACTU) by chlorite and chlorine dioxide were studied in slightly acidic media. The ACTU-ClO(2)(-) reaction has a complex dependence on acid with acid cataly... |
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Formation and structure elucidation of N-(2,3,4-tri-O-acetyl-beta-D-glucopyranosyl)-N'-acetylthiourea.
Carbohydr. Res. 344(1) , 134-5, (2009) Treatment with concd HCl/MeOH transformed N-(tetra-O-acetyl-beta-D-glucopyranosyl)-N'-acetylthiourea, via selective cleavage of the primary alcoholic ester group, into the title compound. |
N-acetyl thiourea |
Acetothiourea |
MFCD00004937 |
1-Acetylthiourea |
Ethanesulfenamide, N-(aminocarbonyl)-1-oxo- |
Urea,1-acetyl-2-thio |
Acetylthiourea |
1-(Acetylsulfanyl)urea |
N'-acetyltbiocarbamide |
N-Acetylthiocarbamide |
EINECS 209-699-9 |
1-ACETYL-2-THIOUREA |
N-acetyl-2-thiourea |
N-ACETYLTHIOUREA |