4',5'-DIBROMOFLUORESCEIN

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Names

[ CAS No. ]:
596-03-2

[ Name ]:
4',5'-DIBROMOFLUORESCEIN

[Synonym ]:
MFCD00005042
EINECS 209-876-0
4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

Chemical & Physical Properties

[ Density]:
2.1 g/cm3

[ Boiling Point ]:
633.7ºC at 760 mmHg

[ Melting Point ]:
270-273 °C(lit.)

[ Molecular Formula ]:
C20H10Br2O5

[ Molecular Weight ]:
490.09800

[ Flash Point ]:
337ºC

[ Exact Mass ]:
487.88900

[ PSA ]:
75.99000

[ LogP ]:
5.19080

[ Index of Refraction ]:
1.771

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5200000
CHEMICAL NAME :
Fluorescein, 4',5'-dibromo-
CAS REGISTRY NUMBER :
596-03-2
BEILSTEIN REFERENCE NO. :
0057189
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H10-Br2-O5
MOLECULAR WEIGHT :
490.12
WISWESSER LINE NOTATION :
T C666 BO EVJ DE IR BVQ& MQ NE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15556 mg/kg/21D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ng/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,116,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1904 No. of Facilities: 237 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 6161 (estimated) No. of Female Employees: 474 (estimated)

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36

[ Safety Phrases ]:
S22-S24/25-S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
LM5200000

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Fluorescein
  • 2-(2,4-Dihydroxybenzoyl)benzoic acid
  • Resorcine
  • Phthalic anhydride

DownStream

  • Spiroisobenzofuran-1(3H),9-9Hxanthen-3-one, 2,4,5-tribromo-3,6-dihydroxy-

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 4',5'-dibromofluorescein
  • 4',5'-dibromofluorescein octadecyl ester
  • 4',5'-Bis(4-aminophenyl)-[1,1':2',1''-terphenyl]-4,4''-diamine
  • 4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-1-ium trifluoroacetate
  • 4', 5'-Bis(3-carboxyphenyl)-[1, 1': 2', 1''-terphenyl]-3, 3''-dicarboxylic acid
  • (6R,7R)-7-[[2-amino-2-(cyclohexen-1-yl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid