4',5'-DIBROMOFLUORESCEIN

Modify Date: 2026-06-30 17:17:06

4',5'-DIBROMOFLUORESCEIN Structure
4',5'-DIBROMOFLUORESCEIN structure
Common Name 4',5'-DIBROMOFLUORESCEIN
CAS Number 596-03-2 Molecular Weight 490.09800
Density 2.1 g/cm3 Boiling Point 633.7ºC at 760 mmHg
Molecular Formula C20H10Br2O5 Melting Point 270-273 °C(lit.)
MSDS Chinese USA Flash Point 337ºC
Symbol GHS06
GHS06
Signal Word Danger

 Use of 4',5'-DIBROMOFLUORESCEIN


4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name 4',5'-Dibromofluorescein
Synonym More Synonyms

 4',5'-DIBROMOFLUORESCEIN Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description 4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].
Related Catalog
References

[1]. Dongdong Yu, et al. An ultrasensitive stain for negative protein detection in SDS-PAGE via 4',5'-Dibromofluorescein. J Proteomics. 2017 Aug 8;165:21-25.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density 2.1 g/cm3
Boiling Point 633.7ºC at 760 mmHg
Melting Point 270-273 °C(lit.)
Molecular Formula C20H10Br2O5
Molecular Weight 490.09800
Flash Point 337ºC
Exact Mass 487.88900
PSA 75.99000
LogP 5.19080
Index of Refraction 1.771
InChIKey ZDTNHRWWURISAA-UHFFFAOYSA-N
SMILES O=C1OC2(c3ccccc31)c1ccc(O)c(Br)c1Oc1c2ccc(O)c1Br

 MSDS

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

 Toxicological Information

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LM5200000
CHEMICAL NAME :
Fluorescein, 4',5'-dibromo-
CAS REGISTRY NUMBER :
596-03-2
BEILSTEIN REFERENCE NO. :
0057189
LAST UPDATED :
199710
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H10-Br2-O5
MOLECULAR WEIGHT :
490.12
WISWESSER LINE NOTATION :
T C666 BO EVJ DE IR BVQ& MQ NE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15556 mg/kg/21D-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Related to Chronic Data - changes in ovarian weight

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ng/plate
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 1,116,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1904 No. of Facilities: 237 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 6161 (estimated) No. of Female Employees: 474 (estimated)

 Safety Information

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements P301 + P310
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes Xi: Irritant;
Risk Phrases R36
Safety Phrases S22-S24/25-S45
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS LM5200000
HS Code 2932999099

 Precursor & DownStream

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor  4

DownStream  1

 Customs

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

MFCD00005042
EINECS 209-876-0
4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one

 4',5'-DIBROMOFLUORESCEIN | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the LogP of 4',5'-Dibromofluorescein?
A: LogP of 4',5'-Dibromofluorescein is 5.19080.
Q: What is the safety information for 4',5'-Dibromofluorescein?
A: Safety information for 4',5'-Dibromofluorescein: S22-S24/25-S45.
Q: What English synonyms does 4',5'-Dibromofluorescein have?
A: English synonyms of 4',5'-Dibromofluorescein: MFCD00005042, EINECS 209-876-0, 4',5'-dibromo-3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one.
Q: What is the English name of 4',5'-Dibromofluorescein?
A: The English name of 4',5'-Dibromofluorescein is 4',5'-Dibromofluorescein.
Q: What is the molecular weight of 4',5'-Dibromofluorescein?
A: Molecular weight of 4',5'-Dibromofluorescein is 490.09800.
Q: What are the downstream products of 4',5'-Dibromofluorescein?
A: Related downstream products(CAS) of 4',5'-Dibromofluorescein: 25709-83-5.
Q: What is the boiling point of 4',5'-Dibromofluorescein?
A: Boiling point of 4',5'-Dibromofluorescein is 633.7ºC at 760 mmHg.
Q: What are the uses of 4',5'-Dibromofluorescein?
A: Main uses of 4',5'-Dibromofluorescein: 4',5'-Dibromofluorescein (Eosinic acid) is a fluorescein derivative that can used as a ligand for studying of protein properties by spectral analysis[1].
Q: What is the polar surface area (PSA) of 4',5'-Dibromofluorescein?
A: Polar surface area (PSA) of 4',5'-Dibromofluorescein is 75.99000.
Q: What is the melting point of 4',5'-Dibromofluorescein?
A: Melting point of 4',5'-Dibromofluorescein is 270-273 °C(lit.).

 4',5'-DIBROMOFLUORESCEINfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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