Fluridone

Suppliers

Names

[ CAS No. ]:
59756-60-4

[ Name ]:
Fluridone

[Synonym ]:
1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one
1-Methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-4(1H)-pyridinone
1-methyl-3-phenyl-5-(α,α,α-trifluoro-m-tolyl)-4-pyridone
Fluridone
Sonar
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]-
Fluridon
Sonar X
1-methyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4-one
1-Methyl-3-phenyl-5-(a,a,a-trifluoro-m-tolyl)-4-pyridone
MFCD00078682
Pride
EINECS 261-916-6
Brake
1-Methyl-3-phenyl-5-[3-(trifluormethyl)phenyl]pyridin-4(1H)-on

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
444.4±45.0 °C at 760 mmHg

[ Melting Point ]:
154-155°C

[ Molecular Formula ]:
C19H14F3NO

[ Molecular Weight ]:
329.316

[ Flash Point ]:
222.6±28.7 °C

[ Exact Mass ]:
329.102753

[ PSA ]:
22.00000

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.568

[ Storage condition ]:
0-6°C

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UU7786500
CHEMICAL NAME :
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-(3-(trifluoromethyl)phenyl)-
CAS REGISTRY NUMBER :
59756-60-4
BEILSTEIN REFERENCE NO. :
1547990
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C19-H14-F3-N-O
MOLECULAR WEIGHT :
329.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>2130 gm/m3/1H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A582,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
>250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,418,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
34908 mg/kg/1Y-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0545242

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H311-H411

[ Precautionary Statements ]:
P273-P280-P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R51/53

[ Safety Phrases ]:
S60-S36/37

[ RIDADR ]:
UN 3077

[ RTECS ]:
UU7786500

[ Packaging Group ]:
III

Synthetic Route

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Related Compounds

  • FLURIDONE
  • 1-[Chloro(4-chlorophenyl)amino]cyclohexanecarbonitrile
  • Dimethyl 5-(benzo[b]thiophen-2-yl)-2,2'-dimethyl-5'-phenyl-[1,1'-bipyrrole]-3,3'-dicarboxylate
  • Ethyl 5-chloro-1-(3-(methoxycarbonyl)-2-methyl-5-phenyl-1H-pyrrol-1-yl)-1H-indole-2-carboxylate
  • (R)-N-((R)-(3,5-Di(naphthalen-2-yl)phenyl)(2-(diphenylphosphanyl)-5-(trifluoromethyl)phenyl)methyl)-N,2-dimethylpropane-2-sulfinamide
  • 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)-5-methoxy-4-methyl-pyridine
  • 2-[rel-(1R,1aS,6aR)-1,1a,6,6a-tetrahydrocyclopropa[a]inden-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 2-(6-Chloro-2-methyl-hex-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  • 4,4,5,5-Tetramethyl-2-[endo-1,7,7-trimethylnorbornan-2-yl]-1,3,2-dioxaborolane
  • 4,4,5,5-Tetramethyl-2-(7-thiaspiro[3.5]nonan-2-yl)-1,3,2-dioxaborolane
  • 5-[trans-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cyclopropyl]pyridine-3-carbonitrile
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