Glabridin

Suppliers

Names

[ Name ]:
Glabridin

[Synonym ]:
1,3-Benzenediol,4-(3,4-dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-,(R)
4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-1,3-benzenediol
Glabridin
Bio-0904
4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol
BIDD:ER0172
4-[(3R)-8,8-Dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]-1,3-benzenediol
1,3-Benzenediol, 4-[(3R)-3,4-dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-3-yl]-
MFCD03427694

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
518.6±50.0 °C at 760 mmHg

[ Melting Point ]:
154-155ºC

[ Molecular Formula ]:
C₂₀H₂₀O₄

[ Molecular Weight ]:
324.37

[ Flash Point ]:
267.4±30.1 °C

[ Exact Mass ]:
324.136169

[ PSA ]:
58.92000

[ LogP ]:
4.26

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
room temp

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Statements ]:
H413

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1,3-Dimethoxybenzene
2',4'-dimethoxyacetophenone
Resorcine
(2,4-Dimethoxyphenyl)acetic acid

DownStream

Customs

[ HS Code ]: 2942000000

Articles

Glabridin inhibits migration and invasion by transcriptional inhibition of matrix metalloproteinase 9 through modulation of NF-κB and AP-1 activity in human liver cancer cells.

Br. J. Pharmacol. 171(12) , 3037-50, (2014)

High mortality and morbidity rates for hepatocellular carcinoma in Taiwan primarily result from uncontrolled tumour metastasis. Glabridin, a prenylated isoflavonoid of licorice (Glycyrrhiza glabra) ro...

Novel phytonutrient contributors to antioxidant protection against cardiovascular disease

Nutrition 28(6) , 605-10, (2012)

The associations linking endothelial inflammation, endothelial oxidative stress, and atherogenesis and the potential for dietary phytonutrients to decrease the impact of these associations were assess...

Glabridin inhibits migration, invasion, and angiogenesis of human non-small cell lung cancer A549 cells by inhibiting the FAK/rho signaling pathway.

Integr. Cancer Ther. 10(4) , 341-9, (2011)

This study reports the antimigration, anti-invasive effect of glabridin, a flavonoid obtained from licorice, in human non-small cell lung cancer A549 cells. Glabridin exhibited effective inhibition of...

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